Magnesium for nocturnal leg crampsdoi:10.1136/dtb.2017.5.0475NoneDrug & Therapeutics Bulletin
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Northeastern who focuses on sleep and adolescent development, meanwhile, says that magnesium can be effective for the approximately half of Americans who are deficient in the mineral. In fact, Mackenzie says she takes magnesium to prevent intense leg cramps that can wake her in the middle of the...
Magnesium supplementation cannot improve the recovery from leg cramps compared to the control group (OR=0.47, 95% CI: 0.14-1.52, P=0.207). Magnesium supplementation had no significant side effects in the treatment group compared to the control group (OR=1.82, 95% CI: 0.90-3.69, P=0.094). ...
Magnesium was not effective for the treatment of nocturnal leg cramps. The period-effect bias probably occurred because of a combination of the natural history of this condition, a regression to the mean, and a true placebo effect.Frusso
Roguin Maor N, Alperin M, Shturman E, et al. Effect of magnesium oxide supplementation on nocturnal leg cramps: a randomized clinical trial. JAMA Intern Med. 2017; 177: 617-623.Maor N R, Alperin M, Shturman E, Khairaldeen H, Friedman M, et al. (2017) Effect of magnesium oxide ...