Synthesis of enantiopure macrocycle-based Cyp-PROTACs Our synthetic approach towards the TWH106 macrocycle requires access to intermediate 7, which can be subsequently macrocyclised in a key intramolecular Heck cross-coupling reaction (Fig. 2). Intermediate 7 was obtained by a convergent route which ...
A separation system using a macrocycle-based ion cnromatographic column provides a fast, effective method for the separation of fluoride in complex matrices. The macrocycle-based system shows better resolution of fluoride than traditional ion cnromatographic methods, separating fluoride from both the ...
Macrocycle-based column for the separation of inorganic cations by ion chromatographyEdwardsB. R.GiauqueA. P.LambJ. D.JOURNAL OF CHROMATOGRAPHY AMacrocyle-based column for the separation of inorganic cations by ion chromatography[J] . Brad R. Edwards,Anthony P. Giauque,John D. Lamb.Journal of...
Self-assembly directed by dinuclear zinc(II) macrocyclic species with 4-aminopyridine, 4-dimethylaminopyridine and isonicotinonitrile produces four novel trans macrocycle-based complexes, namely three molecular stair elements and one one-dimensional (1D) polymeric stair. Controlled synthesis of the cis ...
专利名称：Tetraazabicyclo-macrocycle based manganese chelate compounds suitable as MRI imaging agents 发明人：Meijer, Andreas Richard,Thaning, Mikkel Jacob,Bales, Brian Christopher,Rishel,Michael James 申请号：AU2017382953 申请日：20171221 公开号：AU2017382953A2 公开日：20190912 专利内容由知识产权出版社...
Rapid Synthesis and Antiproliferative Properties of Polyazamacrocycle-Based Bi- and Tetra-Gold(I) Phosphine Dithiocarbamate Complexes A family of bi- and tetrametallic gold(I) phosphine dithiocarbamate complexes were synthesized, starting from cyclam and dimethylcyclam polyazamacrocycles,... O Florès,...
This review provides an outlook on the current application status and main limitations of macrocycles in supramolecular drug delivery systems.doi:10.3390/molecules29163828Yang, YanruiLi, PengchengFeng, HaiboZeng, RuiLi, ShanshanZhang, QixiongMultidisciplinary Digital Publishing InstituteMolecules...
A redox-active M2L2 metalla-macrocycle is depicted, of which construction has been achieved through coordination driven self-assembly from an electron-rich 9-(1,3-dithiol-2-ylidene)fluorene bis-pyridyl ligand and a cis-blocked square planar palladium complex (Pd(dppf)OTf2, dppf = 1,1′-Bis...
Cell-based phospho-Met ELISA EHMES-1 cells (2 × 104cells per well) were seeded in a 96-well black μClear-plate (Greiner Bio-One). After 24 h, the cells were stimulated with hHGF or dimeric macrocycle in RPMI1640 medium supplemented with 10% FBS for 10 min. The cells were was...
In Cu(II) complexes the macrocycle provides N3 donor set for each metal ion, while in the Ni(II) complex alternating N3 and N4 environments of the metal ions are observed. [Display omitted]关键词: Macrocyclic complexes Polynuclear complexes Nickel(II) Copper(II) Crystal structure ...