We subsequently evaluated the diagnostic performance of serological panels, including serum M2BPGi, a fibrosis index based on four factors (FIB-4), aspartate aminotransferase-to-platelet ratio index (APRI), and NAFLD fibrosis score (NFS), in predicting the stage of liver fibrosis. ...
FIB4: Fibrosis index based on four factors; GPR: Gamma- glutamyltranspeptidase to platelet ratio; HA: Hyaluronic acid; HBsAg: Hepatitis B surface antigen; HBV: Hepatitis B virus; HCV: Hepatitis C virus; IQR: Inter- quartile range; LN: Laminin; LSM: Liver stiffness...
There were significant improvements in the spleen index (p < 0.008), AST (p < 0.001), ALT (p < 0.001), platelet count (p < 0.001), albumin (p < 0.001), M2BPGi (p < 0.001), NH3 (p = 0.044), FIB-4 index (p < 0.001), and APRI (p < 0.001) after treatment compared to ...
The levels of M2BPGi were correlated with median ARFI value (P < 0.001), APRI (P = 0.011), and fibrosis 4 index (FIB-4) (P < 0.001). The area under the curve (AUC) of M2BPGi test was 0.58 for F ≥ 1 and 0.68 for F ≥ 2, respectively (P = 0.039 and P = 0.024). ...
index,fibrosis-4(FIB-4)score and liver stiffness measurements(LSM)at baseline and 12 weeks after the end of treatment.Serum M2BPGi levels were measured using enzyme-linked immunosorbent assay.RESULTS All patients achieved sustained virologic response(SVR12)(100%).Serum M2BPGi levels,LSM,FIB-4 ...
FIB-4LiverfibrosisLivertransplantationThe Mac-2-binding protein glycosylation-modified isomer (M2BPGi) is a new marker for progression of hepatic fibrosis. We examined the relationship between serum M2BPGi levels and liver histological findings in patients with biliary atresia (BA) who were not ...