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First, in astrocytes, the modulation of more typical indicators of senescence by m6A still needs to be demonstrated, such as p53/p21, p16, and LaminB1, or the number of positive SA-β-gal in astrocytes. Second, it is necessary to demonstrate whether alterations in m6A levels in AD models...
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Available online: www.leitlinien.de/diabetes (accessed on 13 September 2021). Giandalia, A.; Giuffrida, A.E.; Gembillo, G.; Cucinotta, D.; Squadrito, G.; Santoro, D.; Russo, G.T. Gender Differences in Diabetic Kidney Disease: Focus on Hormonal, Genetic and Clinical Factors. Int. J...
The YASARA program (2021) employed in this study was capable of identifying various primary types of interactions in the considered fibroin–chitosan complexes, such as ionic contacts, hydrogen bonds, and hydrophobic interactions. Of particular significance are strong ionic contacts. These interactions ...
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(SA-β-gal) activity and accumulation of the lipopigment, lipofuscin. Moreover, the cells exhibit a secretory profile associated with cellular senescence known as the senescence-associated secretory phenotype (SASP), which includes IL-6, IL-8 and RANKL. Another unique feature of Cdt-induced OE ...
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