28/08/2012New drug discovery process and clinical evaluation of new drugs. Terminologies, Defining the Research Team; roles, responsibilities, organization structure. Clinical trial Site inititation, subject recruitment, exclusion/inclusion criteria, end-points in clinical trial. Informed Consent formates...
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Cancer Chemotherapy and Pharmacology (2024)Download PDF Associated content Phase 1 study of the ATR inhibitor berzosertib in combination with cisplatin in patients with advanced solid tumours Geoffrey I. Shapiro Robert Wesolowski Timothy A. Yap British Journal of Cancer Article Open Access 26 May...
Gartisertib is an oral inhibitor of ataxia telangiectasia and Rad3-related protein (ATR), a key kinase of the DNA damage response. We aimed to determine the safety and tolerability of gartisertib ± carboplatin in patients with advanced solid tumours. ...
Finally, detailed mechanism as well as adverse effects of CMPD1 should be explored to disclose its pharmacology studies before clinical trials.Abbreviations DDR: DNA damage response MAPK: mitogen-activated protein kinase MK2: MAPK-activated protein kinase 2 FBS: fetal bovine serum DMSO: ...
Malignant hyperthermia: Pharmacology of triggering. Br. J. Anaesth. 2011, 107, 48–56. [Google Scholar] [CrossRef] Hopkins, P.M.; Ellis, F.R.; Halsall, P.J. Evidence for related myopathies in exertional heat stroke and malignant hyperthermia. Lancet 1991, 338, 1491–1492. [Google ...
Department of Pharmacology, College of Medicine, Shaqra University, Shaqra 11961, Saudi Arabia 7 Department of Clinical Pharmacy, College of Pharmacy, King Khalid University, Abha 62529, Saudi Arabia 8 Department of Clinical Nutrition, College of Applied Medical Sciences, Jazan University, Jazan 45142...
J Chin Pharm Sci 2014; 23: 153–8. CAS Google Scholar Qin WJ, Wang YT, Zhang M, Wen RT, Liu Q, Li YL, et al. Molecular chaperone heat shock protein 70 participates in the labile phase of the development of behavioural sensitization induced by a single morphine exposure in mice. ...
Pharm. Pharmacology Students Guiding- Seven (07)M. Pharm. Pharmacology Students Guided- Eighteen (18) My research lab is working on pharmacological investigations in the areas of Alzheimer'sdisease, vascular dementia, neuropathy, opioid dependence, schizophrenia, psychological stress,Huntington's disease...
Spencer - (1947) - Notes on the pharmacology of sodium fluoroacetate - Compound "1.080". J.Am. Pharm. Ass. 36: 59- 62.Ward, Justus C., and Spencer, D. A.: Notes on the pharmacology of sodium fluoroacetate-compound 1080, Jour. Am. Pharm. Assn., XXXVI (2). 59-62,1947....