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Relevance refers to the process of ranking and sorting search results based on importance and usefulness to user’s query. It is determined by a combination of factors such as the content of the results and the search.How does security and privacy work?Security is dependent on the end-user ...
Development and marketing of INCIVEK (telaprevir; VX-950): a first-generation HCV protease inhibitor, in Combination with PEGylated interferon and ribavirin M. Sofia (Ed.), HCV: The Journey from Discovery to a Cure. Topics in Medicinal Chemistry, vol. 31, Springer (2019), pp. 261-291 Cross...
2,3-bisphosphoglycerate (2,3-BPG) produced by the glycolytic pathway facilitates the delivery of oxygen from hemoglobin to the tissues. The Bohr effect is the influence of pH on the release of oxygen from hemoglobin. • In tissues, carbon dioxide diffuses into RBCs and combines with water ...
The crystal structures and properties of boron-silicon (B-Si) compounds under pressure have been systematically explored using particle swarm optimization structure prediction method in combination with first-principles calculations. Thr... X Liang,A Bergara,Y Xie,... - American Physical Society 被引...
166V was detected in more patients after Paxlovid treatment than those after placebo treatment.57This means that SY110 can be used as an alternative drug of Paxlovid or in combination use with Paxlovid in future. Compared with Nirmatrelvir and other reported peptidomimetic Mproinhibitors, SY110...
A combination of experimental and computational analyses revealed that the influence of the metal atom in these complexes is limited to the ability of metal ions to participate in pi interactions with the bdi ligand.Chapter 4 describes the synthesis and characterization of (bdt)M(bdi) and (bds)...
Efflux pumps are widely shown to be important mechanisms responsible for the development of multi-drug resistance in many pathogens. Advances have provided new hope for the design and clinical application of efflux pump inhibitors (EPI) in combination with new antimicrobial drugs to enhance their effi...
In combination, these effects appear to drive DIPG tumorigenesis with a particular efficiency in NSCs compared with other neural progenitor cell types. Discussion Comprehensive large-scale genomic studies of pediatric high-grade gliomas identified H3K27M mutations as a common feature and potential driver...
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