在12月22日的Nature Genetics杂志上发表的一项研究中,阿拉巴马大学伯明翰分校的研究人员表明,一个称作LZTR1的基因突变,与神经鞘瘤这种罕见遗传性疾病的发生相关。 生物通报道:在12月22日的Nature Genetics杂志上发表的一项研究中,阿拉巴马大学伯明翰分校(UAB)的研究人员表明,一个称作LZTR1的基因突变,使人更容易患上一种...
这个基因编码一个btb-kelch超家族成员。最初被描述为一种基于与碱性亮氨酸拉链样家族成员弱同源性的假定转录调节器,随后编码的蛋白质被证明仅局限于高尔基网络,在那里它可能有助于稳定高尔基复合体。该基因缺失可能与Digeorge综合征有关。This gene encodes a membe
该基因缺失可能与Digeorge综合征有关。 This gene encodes a member of the BTB-kelch superfamily. Initially described as a putative transcriptional regulator based on weak homology to members of the basic leucine zipper-like family, the encoded protein subsequently has been shown to localize exclusively ...
transcriptional regulator based on weak homology to members of the basic leucine zipper-like family, the encoded protein subsequently has been shown to localize exclusively to the Golgi network where it may help stabilize the Gogli complex. Deletion of this gene may be associated with DiGeorge ...
这个基因编码一个btb-kelch超家族成员。最初被描述为一种基于与碱性亮氨酸拉链样家族成员弱同源性的假定转录调节器,随后编码的蛋白质被证明仅局限于高尔基网络,在那里它可能有助于稳定高尔基复合体。该基因缺失可能与Digeorge综合征有关。 This gene encodes a member of the BTB-kelch superfamily. Initially describe...
Deletion of this gene may be associated with DiGeorge syndrome.包装清单: 产品编号 产品名称 包装 L28385 pLenti-LZTR1-sgRNA 5µg — 说明书 1份 保存条件:-20℃保存,至少两年有效。注意事项:碧云天拥有sgRNA序列的知识产权,如果需要sgRNA序列,请在订购后发送邮件向info@beyotime.com索取。sgRNA与质粒...
LZTR1Noonan syndromeRASopathiesNoonan syndrome (NS, OMIM 163950) is a common autosomal dominant RASopathy caused mainly by gain﹐f‐function germline pathogenic variants in genes involved in the RAS/MAPK signaling pathway. LZTR1 gene has been associated with both dominant and recessive NS. Here, ...
Deletion of this gene may be associated with DiGeorge syndrome. 产品名称 LZTR1 Knockout HEK293T Cells 说明书 包装 1支/瓶 1份 保存条件: 对于细胞培养瓶或离心管运输的活细胞,室温3-5天有效;对于干冰运输的冻存细胞,液氮保存,长期有效. 注意事项: 碧云天拥有sgRNA序列的知识产权,如果需要sgRNA序列,...
Gene ID (NCBI) 8216 Alternative Names BTBD29;LZTR-1;NS10;SWNTS2 Application Notes: The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user. WB 1:500 - 1:2000
[27] Kurahashi H, Akagi K, Inazawa J, et al. Isolation and characterization of a novel gene deleted in DiGeorge syndrome[J]. Hum Mol Genet, 1995,4(4):541-549. DOI: 10.1093/hmg/4.4.541. [28] Piotrowski A, Xi...