lysyl oxidase deficiency 专业医学词典 赖氨酸氧化酶缺乏症 与"lysyl oxidase deficiency"相近的词条 ... lysyl bradykinin、lysyl-bradykinin lysyl group lysyl hydroxylase lysyl-lysine lysyl oxidase lysyl oxidase deficiency lysyl residue lysyl-tRNA synthetase lysylalanine Lysylaminoadenoside lysylaminoadenosine lysy...
Lysyl oxidase deficiency in lung and fibroblasts from mice with hereditary emphysema. Biochem Biophys Res Commun. 1977; 78:706-12. [PubMed: 20889]Starcher BC, Madaras JA, Tepper AS (1977): Lysyl oxidase deficiency in lung and fibroblasts from mice with hereditary emphysema. Biochem Biophys ...
Lysyl oxidase (LOX) catalyzes cross-linking of elastin and collagen, which is essential for the structural integrity and function of bone tissue. The present study examined the role of Lox gene deficiency for the osteoblast phenotype in primary calvarial osteoblasts from E18.5 Lox knockout ( Lox ...
Lysyl oxidase deficiency: a new cause of human arterial dissection. Heart 91, e33 (2005). Article CAS PubMed PubMed Central Google Scholar Kraft-Sheleg, O. et al. Localized LoxL3-dependent fibronectin oxidation regulates myofiber stretch and integrin-mediated adhesion. Dev. Cell 36, 550–561...
Lysyl oxidase (lox) gene deficiency affects osteoblastic phenotype Calcif Tissue Int, 85 (2) (2009), pp. 119-126 CrossrefView in ScopusGoogle Scholar 96 M Bignon, C Pichol-Thievend, J Hardouin, et al. Lysyl oxidase-like protein-2 regulates sprouting angiogenesis and type IV collagen assemb...
Properties and function of lysyl oxidase. Am J Respir Cell Mol Biol 1991;5:206–210. 14. Uzel M, Scott I, Babakhanlou-Chase H, et al. Multiple bone morpho- genetic protein 1-related mammalian metalloproteinases process pro- lysyl oxidase at the correct physiological site and control lysyl ...
Lysyl oxidase deficiency in Ehlers-Danlos syndrome type V. Connect Tissue Res 1975;3:49-53.Di Ferrante N, Leachman RD, Angelini P, Donnelly PV, Francis G, Almazan A. Lysyl oxidase deficiency in Ehlers-Danlos syndrome type V. Connect Tissue Res. 1975;3:49-53....
Since clinical abnormalities in these disorders have been noted as a result of deranged biosynthesis in both elastin and collagen with lysyl oxidase deficiency, it seemed appropriate to define the substrate specificity of highly purified lysyl oxidase in more detail and to determine whether the same ...
lysyl oxidase 医学辞典 赖氨酰〔基〕氧化酶:氧化还原酶类的一种,催化赖氨酸+O2=ε-醛基赖氨酸+NH3+H2O的反应,需要Cu 2+ 和磷酸吡哆醛。本反应是形成胶原蛋白和弹性蛋白的共价交联的一个步骤。此酶缺陷或缺如可致Ehlers-Danlos综合征V型和皮肤松弛(cutis laxa) 英汉医学词典 赖氨酰氧化酶 ...
Lysyl oxidase (LOX) is a copper-dependent enzyme that initiates covalent crosslinking of elastin precursors by oxidizing peptidyl lysine to aminoadipic semi-aldehydes. Previous studies have shown LOX deficiency to affect crosslinking of elastin and collagen in vivo, resulting in disorganized connective ...