Lysyl oxidase copper-talon complex: a model. Biochim Biophys Acta 1993;1202:7-12.Krebs, C. J. and Krawetz, S. A. (1993) Lysyl oxidase copper-talon complex : a model. Biochim. Biophys. Acta 1202, 7-12Krebs, C. J. and Krawetz, S. A. (1993) Lysyl oxidase copper-talon complex: ...
Lysyl oxidase: a potential target for cancer therapyLysyl oxidases (LysOX; EC 1.4.3.13, protein-lysine 6-oxidases) are extracellular copper enzymes that catalyze the cross-linking of collagens or elastin in the extracellular matrix (ECM), thereby r ...Lysyl oxidases...
CopperPQQBenzylamine oxidase from Pichia pastoris is a copper containing quino-protein with a molecular weight of 106 kdal. It catalyzes the oxidative deamination of primary amines and diamines. Its most unusual feature is the oxidation of 蔚-aminogroups in peptidyllysine residues. This reaction is...
It has also been demonstrated that in copper-deficient pigs, which exhibit these defects, there is a dramatic decrease in plasma amine oxidase activity (Blaschko et al., 1965). On the basis of these findings it was suggested (Page & Benditt, 1967) that lysyl oxidase may belong to that ...
lysyl oxidasecollagen fibrilscleral biomechanicsPurpose: Scleral remodeling causes the excessive ocular elongation that underlies myopia. Lysyl oxidase (LOX), a copper-containing amine oxidase, can catalyze collagen and elastin crosslinking. The purpose of this study was to investigate the role of LOX ...
Lysyloxidaseisanextracellularcopperenzymethatcatalyzestheconversionoflysineresiduesincollagen andelastinintoaldehydes,whicharehighlyreactive.Thesealdehydesspontaneouslyreactwithother aldehyderesiduesderivedfromlysyloxidaseorunmodifiedlysineresidues,resultingincross-linkingof ...
Molecules that are highly expressed in tumour endothelial cells (TECs) may be candidates for specifically targeting TECs. Using DNA microarray analysis, we found that the lysyl oxidase (LOX) gene was upregulated in TECs compared with its expression in no
Lysyl oxidase (LOX) is a copper-dependent extracellular, matrix-embedded amine oxidase protein that plays a critical role in covalent cross-linking of fibrillar collagens and elastin (17, 18). There are a total of five LOX isoforms identified to date: LOX and the LOX-like (LOXL) enzymes 1...
必应词典为您提供lysyl-oxidase的释义,n. 赖氨酸氧化酶; 网络释义: 赖氨酰氧化酶;赖氨酰氧化酶基因;胺基氧化酶;
Lysyl oxidase (LOX), the copper-dependent extracellular enzyme, plays a critical role in the regulation of protein cross-linking in the extracellular matrix (ECM). It is also involved in liver regeneration and liver fibrosis. However, the mechanism of LOX regulation in mouse hepatocytes is still...