Twitter Google Share on Facebook lysosome Thesaurus Medical Encyclopedia Wikipedia Related to lysosome:primary lysosome ly·so·some (lī′sə-sōm′) n. A membrane-bound organelle in the cytoplasm of most cells containing various hydrolytic enzymes that function in intracellular digestion. ...
A single-membrane vesicle that forms at a late stage of the autophagic pathway by fusion of autophagosomes with endosomes or lysosomes and that contains degradative enzymes obtained after fusion. Periodontis A common inflammatory disease of the supporting tissues of the teeth that leads to resorption...
inside the cell that performs a specific function. In this case, there are two types of organelles: (1)membrane-bound organelles(included are double-membraned and single-membraned cytoplasmic structures) and (2)non-membrane-bound organelles. Examples of membrane-bound organelles arenucleus,...
Autophagy is a major intracellular degradation system that derives its degradative abilities from the lysosome. The most well-studied form of autophagy is macroautophagy, which delivers cytoplasmic material to lysosomes via the double-membraned autophago
The coat-color phenotype of young homozygous double-mutant mice deficient in subunits of BLOC-3 (HPS1) and BLOC-1 (pallidin) was indistinguishable from that of BLOC-1 single mutants. Taken together, these observations suggest that HPS1 and HPS4 are components of a protein complex that ...
About 60 years ago, Belgian cytologist Christian de Duve discovered that animal cells contained small 0.1–1.2 μm organelles limited by a single membrane and containing acidic hydrolases, active at pH ~4.5. The lysosome (from the Greek lysis, to separate and soma, body) is the subcel...
One can propose: (1) deficiencies of a single lysosomal hydrolase (also including deficiencies of sphingolipid activator proteins); (2) multiple hydrolase deficiencies secondary to the default of a co- or posttranslational maturation step; (3) deficiencies in lysosomal membrane transporters for small ...
Lysosome-associated membrane protein-2 polyclonal antibody 溶酶体相关膜蛋白-2, 多抗 品牌:Enzo CAS No.: 储存条件:-20℃ 纯度:– 产品编号 (生产商编号) 等级规格运输包装零售价(RMB)库存情况参考值 ALX-210-206-R100 –100 µl–10,640.00–– ...
(d) Quantification of per cent cell area occupied by double-membrane autophagosomes and single-membrane autolysosomes in control and V1H-depleted cells under starvation conditions. Error bars mark s.e.m., N=3 animals, 15 images analysed for each genotype. ***P<0.001, Student’s t-test. ...
Structurally they appear as dense spheres or tubes generally less than one micron across, though the size and number are variable depending on the amount of unprocessed cellular debris that has been taken up. The organelle has a single phospholipid bilayer membrane and an acidic (pH 4.5) ...