Lysosomal cathepsin B,: partial characterization in rat preputial gland and recompartmentation to estradiol-17-beta - J, Smith - 1976 () Citation Context ...umor. The mucosa was then separated from the muscle layer, (9) has largely been traced to a cathepsin B-like cysteine pro serosa, ...
Lysosomal enzyme cathepsin B enhances the aggregate forming activity of exogenous α-synuclein fibrils. Neurobiol Dis. 2015;73:244–53. https://doi.org/10.1016/j.nbd.2014.10.011. Article CAS PubMed Google Scholar Sacino AN, Brooks MM, Chakrabarty P, et al. Proteolysis of α-synuclein ...
Google Share on Facebook lysosome (redirected fromLysosomal enzymes) Thesaurus Medical Encyclopedia ly·so·some (lī′sə-sōm′) n. A membrane-bound organelle in the cytoplasm of most cells containing various hydrolytic enzymes that function in intracellular digestion. ...
and to functionally characterize the role of catB in relation to lysosome function and α-syn clearance. We first provide genetic evidence that PD-associatedCTSBvariants decrease expression levels of the enzyme. Second, by pharmacologically and genetically modulating catB expression...
In addition, FOY and FOY 305 were found to significantly decrease the subcellular redistribution of cathepsin B that occurs in both models. These findings indicate that enzyme activity sensitive to inhibition by FOY and FOY 305 may be critical to the redistribution phenomenon that characterizes both ...
Despite their altered positioning, those dispersed structures remain overall functional: (i) the trafficking and maturation of the lysosomal enzyme cathepsin B is not altered; (ii) the autophagic flux, ending up in the degradation of autophagic substrate inside lysosomes, is stimulated. Consequently, ...
关键词: Cathepsin B Lysosomal phospholipidosis Azithromycin Gentamicin Lysosomal enzyme hyperactivity DOI: 10.1016/0014-5793(96)00975-1 被引量: 51 年份: 1996 收藏 引用 批量引用 报错 分享 全部来源 免费下载 求助全文 全文购买 Elsevier (全网免费下载) Elsevier Wiley Wiley 掌桥科研 查看更多 相似文献 ...
Cathepsin in Lysosomes and Its Roles during Muscle Aging; 溶酶体中的组织蛋白酶及其在肌肉成熟中的作用 3. Investigation on ultrastractural change of lysosome related with oolemmagenesis in the oogenesis of Mystus macropterus (Bleaker); 大鳍鳠卵发生中溶酶体超微结构变化与卵膜发生 更多例句>> 4...
et al. Deficiency of UDP-N-acetylglucosamine: lysosomal enzyme N-acetylglucosamine-1-phosphotransferase in organs of I-cell patients. Biochem. Biophys. Res. Commun. 105, 1052–1058 (1982). Article CAS PubMed Google Scholar Reitman, M. L., Varki, A. & Kornfeld, S. Fibroblasts from ...
RESULTS: The trabecular meshwork from all the eyes stained intensely against antibodies to cathepsins B and G and alpha 1-proteinase inhibitor. The staining for elastase was weaker but evident. Image analyses revealed that the staining intensity for each protease or inhibitor was similar in all ...