Lysosomal acid lipase (LAL) activity, measured with 4-methyl-umbelliferyl oleate as substrate, is present in high concentration in lymphocytes and monocytes, but not in polymorphonuclear leukocytes. Lymphocytes were isolated from whole blood samples by modification of the Ficoll-Isopaque method of B8...
Define lysosomal. lysosomal synonyms, lysosomal pronunciation, lysosomal translation, English dictionary definition of lysosomal. n. A membrane-bound organelle in the cytoplasm of most cells containing various hydrolytic enzymes that function in intracel
Dictionary Medical Encyclopedia Related to lysosomal:Lysosomal enzymes Graphic Thesaurus🔍 DisplayON AnimationON Legend Synonym Antonym Related </>embed</> organelle cell organelle cell organ lysosome noun Words related to lysosome nounan organelle found in the cytoplasm of most cells (especially in leu...
Lysosomal acid lipase activity was measured using the fluorogenic substrate 4-methyl-umbelliferyloleate (100 mg ml−1 in DMSO). Control or TFEB-TG macrophages were lysed in buffer (10 mM Tris pH 8; 50 mM NaCl; 1% Triton X-100) containing protease inhibitors and protein concentrati...
The ascorbic acid induced nonenzymic lipid peroxidation was distributed in all the subcellular fractions wit... S Bishayee,AS Balasubramanian - 《Journal of Neurochemistry》 被引量: 85发表: 2010年 PHOSPHOLIPID METABOLISM IN EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS: ACTIVITY OF MITOCHONDRIAL PHOSPHOLIPASE A2...
In the blastocyst, acid phosphatase activity was confined to vesicles and occasionally to microv... R Abraham,R Hendy,WJ Dougherty,... - 《Experimental & Molecular Pathology》 被引量: 36发表: 1970年 The cAMP-responsive element binding protein (CREB) transcription factor regulates furin expression...
Lysosomal Acid lipase deficiency infantile and childhood/adult types (cholesterol esters, triglycerides) Pompe disease (glycogen storage disease type II) Danon disease (glycogen) Cystinosis (cystine) Tables A and B show theLSDs, defective enzyme, gene, and the accumulated substrate. The reader shoul...
As shown in Figures 4a and b, the first three fractions of the purification contained most of the Lamp-1 protein and acid phosphatase activity but no Bax protein. The majority of Bax and Bak were present in fractions expressing high amounts of mitochondrial COX IV (fractions 5–8). Here ...
(PGC1α). AMPK decreases lipogenesis and cholesterol synthesis by inhibiting acetyl-CoA carboxylase (ACC) and HMG-CoA reductase (HMGR). Conversely, AMPK activates adipose triglyceride lipase (ATGL) for lipolysis and facilitates mitochondrial fatty acid uptake for β-oxidation by reducing an allosteric...
Effect of acidic phospholipids on the activity of lysosomal phospholipases and on their inhibition by aminoglycoside antibiotics--i. Biochemical analysis. Biochem. Pharmacol. 1990, 40, 489–497. [Google Scholar] [CrossRef] Nudelman, I.; Rebibo-Sabbah, A.; Shallom-Shezifi, D.; Hainrichson, ...