Safety information regarding Fmoc-L-Lys(Dde)-OH is not available. Applicable Fields Peptide Synthesis: Fmoc-L-Lys(Dde)-OH is commonly used in peptide synthesis. Its purpose in this field involves its ability to protect the amino group of lysine, allowing for selective deprotection and ...
Quasi-orthogonally-protected Lys derivative. The Fmoc group can be removed selectively by treatment with piperidine; the Dde group is cleaved with 2% hydrazine in DMF [1]. When removing Dde in the presence of allyl-based protecting groups, allyl alcohol should be included in the deprotection solu...