Prognosis is bleak, with a 10% 5-year survival rate. In this report, we present the case of a 20-year-old man from French Polynesia, referred for F-18-FDG PET/CT because of the progressive worsening of febrile cutaneous-mucosal infiltration on the face persisting for 1 month. PET ...
Eighty-four publications were included, 83% published after 2017. Southern and Eastern Africa led in output. Most studies were chart reviews (47.6%) and cohort studies (25%). NHL accounted for over 80% of cases, with an age-standardized rate (ASR) reaching 10.9/100,000, while HL had an...
Of 126 patients who received reduced intensity conditioning with sirolimus (n = 103) or with standard regimens (n = 23), the 3-year overall survival rate was 66% (p = 0.007 vs no sirolimus) in the sirolimus arm and 38% in the no-sirolimus group with a corresponding 3-year progression...
A Survival analysis for low and high PSI scores patients in the anti-PD-L1 immunotherapy cohort using KM curves (IMvigor210 cohort; log-rank test, P = 0.012). B KM survival analysis for low and high PSI scores groups in the anti-PD1 immunotherapy cohort (GSE78220 cohort; log-rank ...
With the introduction of the HLH-94/2004 treatment regimen as a bridge to allo-HSCT treatment, the outcome of primary HLH has improved to a 5-year survival rate of 50%–70%.2 Epstein–Barr virus (EBV)-HLH is the most common and severe form of secondary HLH and is prevalent among ...
Additional efficacy end points of interest included the best objective response rate (ORR), best CRR, overall survival (OS), and duration of response (DOR). OS was defined as the time from infusion to death from any cause. DOR was defined as the time from first response, defined as ...
Kaplan-Meier survival estimates according to age in 50 ALK-DLBCL cases from the literature. Full size image In regards of sex distribution, the male to female ratio was 3:1; female cases accounted for 23% of the cases. In pediatric cases, the male to female ratio was 1.8:1 and in adul...
Besides, the survival rate of lymphoma cells declines after MALAT-1 knockdown in drug-resistant cell lines, the proportion of cells in the G2/M phase decreases, and the expression levels of LC3-II/LC3-I increases and the expression level of p62 protein decreases, suggesting that inhibiting ...
initial response, the estimated relapse-free survival rate was 65%, indicating a durable response with tisagenlecleucel [12]. Compared with historic data, these CAR T cell products have offered unexpected durable responses in patients with heavily pretreated DLBCL [14], which promoted the approval...
in the analysis. Patients were stratified into four quartiles based on YY1 expression levels. For further comparison, the top 25% and bottom 25% of patients were specifically analyzed. The statistical significance of survival differences between these two groups was evaluated using the log-rank ...