Stacker, Lymphatic vessels in cancer metastasis: bridging the gaps. Carcinogenesis, 2006. 27(9): p. 1729-38.Shayan, R., Achen, M. G., Stacker, S. A., Lymphatic vessels in cancer metastasis: bridging the gaps. Carcinogenesis 2006, 27, 1729-1738....
The generation of new lymphatic vessels through lymphangiogenesis and the remodelling of existing lymphatics are thought to be important steps in cancer metastasis. The past decade has been exciting in terms of research into the molecular and cellular biology of lymphatic vessels in cancer, and it ...
Interaction of tumor cells and lymphatic vessels in cancer progression. Oncogene 31, 4499–4508 (2012). 18. Kim, U., Park, H. C. & Choi, K. H. Differential permeability of lymphatic and blood vessels in determining the route of metastasis as demonstrated by indirect lymphography. Clin Exp...
meanwhile tumor-derived growth factors stimulate intratumoral and peritumoral lymphangiogenesis, facilitating lymphovascular invasion (LVI) to remodel tumor microenvironment (TME) [16]. Cancer cells that invade lymphatic vessels spread into tumor-draining lymph nodes...
Lymphatic vessels were easily found in the whole wall of normal stomach with LMVD 6.93±1.32,while lymphatic vessels in cancerous tissues were fewer(LMVD 5.83±3.26)with narrower lumens,lymphatic vessels in pericancerous tissues more than those of normal tissues(LMVD 11.89±3.95)with dilated lumens...
Colonic CarcinomaFactor-8Lymphatic VesselsLYVE-1Venous VesselsObjective: Colonic carcinomasspread to regional lymph nodes and liver. There are cancer-associated lymphaticand venous vessels at the margin of colonic carcinomas, which facilitate spreadingcarcinoma through lymphatic and venous vessels. This ...
The lymphatic vessels are also crucially involved in the pathogenesis of diseases such as tumor metastasis, lymphedema, and various inflammatory conditions. ... T Karpanen,K Alitalo - 《Annu Rev Pathol》 被引量: 562发表: 2008年 Molecular mechanisms of lymphangiogenesis in development and cancer The...
International Journal of CancerBirner P,Schindl M,Obermair A,et al.Lymphatic microvessel density as a novel prognostic factor in early-stage invasive cervical cancer. International Journal of Cancer . 2001Lymphatic mi-crovessel density as a novel prognostic factor in early-stage invasive cervical ...
Recently, it has been revealed that lymphangiogenic growth factor VEGF-C and its receptor Flt-4 play an important role for invasion and metastasis in cancer cells.To examine VEGF-C expression and its correlation with lymphatic status, including the number of lymph vessels and lymphatic invasion, ...
Thirty-four patients (10.2%) had metastatic lymphatic spread: 13 exclusively in the lymphatic vessels close to the tumor, 17 in at least 1 lymph node, and 4 in both the lymphatic vessels and nodes. The rate of lymph node involvement (regardless of lymphatic vessel involvement) correlated ...