The diagnosis of Lyme neuroborreliosis must be validated with evidence of antibody production against Borrelia burgdorferi in the CSF, shown by a higher titer of antibody in the CSF than in the serum. The most helpful CSF test is intrathecal production of specific antibodies. This test is run o...
A detectable level of color is thereby achieved even when the serum has a low analyte-antibody titer. The assay of the invention requires only 90 seconds to complete and has no time-critical steps as compared to 6.5 minutes and three time-critical steps for IMMUNOCLONE TM . Accordingly, many...