The disease has been reported in the Northeast, Mid-Atlantic, North Central, and Pacific coastal regions of the United States (see map) and in Europe, where it was first described almost 100 years ago. It is most prevalent in the northeastern and Midwestern states of the U.S., with about...
Map by Geology.com using data from the Center for Disease Control. Geographic Range of Blacklegged Ticks The blacklegged tick has a geographic range across the eastern and southeastern United States and in the Great Lakes region. The western blacklegged tick has a range that spans the Pacific ...
It is an infectious disease caused by a spirochete, B. burgdorferi, which is transmitted chiefly by I. dammini and pacificus ticks in the United States and I. ricinis in Europe. It is a disease with early and late cutaneous manifestations plus involvement of the nervous system, heart, eye,...
In Europe, Lyme neuroborreliosis (LNB) is the most severe manifestation of Lyme borreliosis and has recently been added to the communicable disease surveillance list for EU/EEA by the European Commission. In Northern Europe, LNB is primarily caused by the spirocheteBorrelia gariniiand transmitted by...
burgdorferi infection has been the mainstay of laboratory confirmation of Lyme disease for over 20 years. A two-tiered serology algorithm, which utilizes a first-tier EIA followed by a second-tier WB or IB assay, was recommended in the United States and Europe(Fig. 2A)13,14. Contemporary ...
A mouse model for Borrelia burgdorferi infection: approach to a vaccine against Lyme disease Lyme disease is the most common vector-transmitted illness in the USA and Europe. The pathogen, Borrelia burgdorferi, causes a complex spectrum of disease that affects the skin, joints, nervous system and...
Here we examine the impact of host migration on the spread of a tick-borne zoonotic disease, using Lyme Borreliosis (LB) spirochaetal species in Europe. We demonstrate that the migration of the LB species is dependent on and limited by the migration of their respective hosts. We note that...
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Europe and Asia. Lyme disease is the most prevalent vector-borne disease in the northern hemisphere1. In the USA, 22,014 confirmed human cases were reported in 2012 (ref.2), with∼10-fold more infections suspected3. In Europe,∼65,500 Lyme borreliosis patients are documented annually4. ...
Lyme disease, defined by erythema chronicum migrans and sometimes followed by neurologic, cardiac, or joint involvement, is known to have affected 512 pati... STEERE,C Allen - 《Annals of Internal Medicine》 被引量: 657发表: 1979年 Physical map of the linear chromosome of the bacterium Borrel...