Ly6G 高是粒细胞来自样；Ly6c高是单核细胞样 这两种抗原都属于G360问答r-1,一般还会做一个CD11b ...
Ly6G 高是粒细胞样；Ly6c高是单核细胞样 这两种抗原都属于Gr-1,一般还会做一个CD11b
The evidence that conventional Ly6G/Ly6C marker analysis may not be suited to study of inflammation-induced MDSCs led to the development of a novel ... J Bei,C Zhao,G Li,... - 《Mediators of Inflammation》 被引量: 4发表: 2017年 加载更多研究...
Since loss of Ly6C is an important marker of differentiation to CX3CR1vessel patrolling monocytes or CX3CR1MHCIIintestinal macrophages, we speculate that NF-κB dependent loss of Ly6Ccells during NEC exposure may affect the intestinal homeostasis including the microvasculature thus predisposing to NE...
However, CD11b+/Ly6C+ cells were found in the peritoneal cavity at 2-wpi, and some expressed the macrophage marker F4/80 (Fig. 2a) At 8 and 12 weeks the majority of F480+PD-L2+ cells expressed medium levels of Ly6C, suggesting that a Ly6C+ population converts into mature macrophages...
However, these two cell types can be difficult to differentiate because of shared surface marker expression. Here we describe a more refined approach to distinguish MDSCs from PMNs utilizing the integrin receptor CD11b combined with conventional Ly6G and Ly6C expression. This approach separated the ...
The high resemblance in surface marker profile and gene expression signature between these proinflammatory lamina propria cells and the CX3CR1intLy6Chi effector monocytes described here suggests that these cells might be identical. Studies like the present can, through providing a high-resolution ...
2h). Local activation and cytotoxicity marker expression of recruited CD8+ T cells and NK cells was diminished in the HFHCD group as confirmed by the detection of membrane marker CD44 and Granzyme B (Fig. 2i). No difference was observed in PD-1 and PDL-1 expression on infiltrating myeloid...
at CiOA day 7 when compared to saline-injected controls.f,gMonocyte marker Ly6C, and the more monocyte-subset-specific markers, CCR2 (Ly6Chigh) and CX3CR1 (Ly6Clow) are strongly induced (f), together with the monocyte attracting chemokines CCL2 (Ly6Chigh) and CX3CL1 (Ly6Clow) (g) ...
(Mice are pooled from at least 3 independent experiments; median is indicated in black, and Kruskal-Wallis with Dunn's multicomparison test is performed.) (H) Bar graphs show the respective marker expression (as mean fluorescence intensity [MFI]) on intravascular BM monocytes (CD45+ cells ...