HFD小鼠肺巨噬细胞总体AAMs比例增加,导致释放的CXCL1减少,因此气道中性粒细胞减少。 5、膳食纤维通过激活CD8+ T细胞增强抗病毒免疫 为了确定适应性免疫抗病毒反应是否也被膳食纤维改变,研究评估了CD8+ T细胞在感染过程中的反应。虽然总淋巴细胞数和CD8+ T细胞数没有变化,但是HFD小鼠的CD8+ T细胞活性更强,主要表现为C...
cDCs可进一步分为两个表型和功能不同的亚群,DC1和DC2在小鼠中,DC1s表达高度特异性的标记物,包括XCR1和Clec9a,发育依赖于转录因子如IRF8、BATF3和ZFP366,擅长将细胞内病原体和自身抗原交叉呈递给主要的细胞毒性CD8+T细胞,从而在抗病...
(2011) Ly6C supports preferential homing of central memory CD8(+) T cells into lymph nodes, Eur J Immunol 41, 634-644.Hanninen A, Maksimow M, Alam C, Morgan DJ, Jalkanen S. Ly6C supports preferential homing of central memory CD8+ T cells into lymph nodes. Eur J Immunol 2011 ...
production in CD8 T cells and the homing of CD8 T cells. In addition, Ly-6C may act as a signaling molecule of LFA-1 activation. 淋巴细胞抗原Ly6c抗体品牌 现货供应,质量有保证、价格优惠、实验效果好,同时我司为您提供*新价格、说明书、规格、用途、实验原理等相关操作说明,欢迎前来选购! 淋巴细胞...
结果显示,2DG处理显著降低了4T1和4T07肿瘤小鼠脾脏中G-MDSC细胞的比例,特别是Ly6Glow亚群,并提高了CD4+T细胞和CD8a+T细胞的水平(图8B1-8B2)。与4T1-16d组相比,2DG处理的4T1或4T07荷瘤小鼠脾脏中CD3e+CD44lowCD62L+T细胞比例成...
CD8+ T cellAdjuvants are considered a necessary component for HBV therapeutic vaccines but few are licensed in clinical practice due to concerns about safety or efficiency. In our recent study, we established that a combination protocol of 3-day pretreatments with GM-CSF before a vaccination (...
今日分享的文献乃是作者对众多文献实验予以总结后,于检测小鼠脾细胞髓系细胞群体时所遇共性难题的深度剖析与有效解决之道。该文献系 12 年发表,虽历时已久,然其经典价值恒在,值得当下借鉴。文中有两大创新亮点。其一,以 Ly6C/Ly6G 检测髓系分群相较 Gr-1 更具优势;其二,在检测髓系细胞时,F4/80 并非必需抗体...
体内单克隆抗体抗小鼠CD8αBXC-BE0075-1mg查看 体内单克隆抗体抗小鼠 Ly6G/Ly6C(Gr-1)规格: 同种型大鼠IgG2b, κ 推荐的同种型对照体内MAb大鼠IgG2b同种型对照,抗锁孔帽贝血蓝蛋白 推荐的稀释缓冲液体内纯 pH 7.0 稀释缓冲液 免疫原小鼠粒细胞 报告的应用程序体内Gr-1+ 髓系细胞耗竭 流式细胞 ...
For suppressive proliferation assay, MDSC (CD11b+Ly6C+Ly6G+) enriched cells were obtained from spleen of tumor-bearing mice by magnetic sort (Myeloid-Derived Suppressor Cell Isolation Kit, Miltenyi). CD8 T cells were isolated from spleen of OT-I mice by magnetic sort (CD8a + T Cell Isol...
production in CD8 T cells and the homing of CD8 T cells. In addition, Ly-6C may act as a signaling molecule of LFA-1 activation. Also known as: Ly6c; Ly 6c; Ly6c protein;Anti-CD59/Ly6c抗体Ly-6C; Ly6c1; Ly6c2; Lymphocyte antigen 6 complex; Lymphocyte antigen 6 complex locus C; ...