英文名：LY294002;LY-294002；PI3-kinase inhibitor CAS号：154447-36-6 结构式：O=C1C=C(OC2=C1C=CC=C2C3=CC=CC=C3)N4CCOCC4 分子式：C19H17NO3 分子量：307.34 闪点 ：253.0±28.7 °C 熔点：183-185℃ 沸点：494.6±45.0 °C at 760 mmHg 极化度：34.1±0.5 10-24cm3 密度 ：1.3...
LY 294002试剂CAS号:154447-36-6保存条件:RT产品介绍:PI 3-Kinase inhibitor上海惠诚生物为广大科研用户提供科学仪器,试剂耗材等专业科研产品服务。 代理产品品牌有:Nu-chek、LKT、AccuStandard、APSC、MPBio、Sigma-Aldrich、NIST,Reagecon、Megazyme,LGC、Ultra,日本和光(WAKO)、Shodex,Dr.E、PSS ,Matreya,CaroteNat...
英文名:LY294002;LY-294002;PI3-kinase inhibitor CAS号:154447-36-6 结构式:O=C1C=C(OC2=C1C=CC=C2C3=CC=CC=C3)N4CCOCC4 分子式:C19H17NO3 分子量:307.34 闪点:253.0±28.7 °C 熔点:183-185℃ 沸点:494.6±45.0 °C at 760 mmHg 极化度:34.1±0.5 10-24cm3 密度:1.3±0.1 g/cm3 蒸汽压:...
[5]. Md Mokhtar AH, et al. LY294002, a PI3K pathway inhibitor, prevents leptin-induced adverse effects on spermatozoa in Sprague-Dawley rats. Andrologia. 2019 Apr;51(3):e13196. [6]. Yi-Jen Hsueh, et al. Lysophosphatidic acid induces YAP-promoted proliferation of human corneal endothelial ...
(PI3 Kinase Inhibitor)体内是一种特异性抑制剂。它可以特异地抑制PI3 kinase的活性,但是不影响其他蛋白激酶活性。研宄表明抑制剂LY294002可以抑制PI3K-依赖的Akt磷酸化和激酶活性,它通过和ATP竞争PI3K催化结构域的结合位点发挥作用,从而抑制其下游分子Akt的磷酸化,此抑制剂已被广泛应用与信号传导通路的作用研宄中。本...
LY294002 is a potent and specific cell-permeable inhibitor of phosphatidylinositol 3-kinase (PI3-kinase). Format/Formulation:Lyophilized 仅供科研使用。不可用于诊断程序。 规格 基因ID (Entrez)5294 纯化方法薄层层析 运输条件干冰 比抑制或靶标PI3-激酶 ...
LY294002 (SF 1101) is a broad-spectrum inhibitor of PI3K, inhibiting PI3Kα, PI3Kδ, and PI3Kβ (IC50=0.5/0.57/0.97 μM). LY294002 is also an inhibitor of DNA-PK (IC50=1.4 μM) and an inhibitor of CK2 (IC50=98 nM). LY294002 activates apoptosis and autophagy. ...
PI3K抑制剂(LY294002) 英文名称:PI3K Inhibitor产品规格:1mg|5mg|25mg发货周期:1～3天产品价格:询价本产品仅可用于科研实验,严禁用于其他非科研用途!LY294002是一种常用的phosphatidylinositol 3-kinase (PI3K)抑制剂。LY294002可以通透细胞,特异性抑制PI3K,抑制PI3K/Akt信号途径,包括常见的抑制Akt磷酸化等。LY294...
[2]. Gharbi SI, et al. Exploring the specificity of the PI3K family inhibitor LY294002. Biochem J. 2007 May 15;404(1):15-21. [3]. Davidson D, et al. Small Molecules, Inhibitors of DNA-PK, Targeting DNA Repair, and Beyond. Front Pharmacol. 2013 Jan 31;4:5. ...
[2].Gharbi SI, et al. Exploring the specificity of the PI3K family inhibitor LY294002. Biochem J. 2007 May 15;404(1):15-21. [3].Jiang H, et al. Phosphatidylinositol 3-kinase inhibitor(LY294002) induces apoptosis of human nasopharyngeal carcinoma invitro and in vivo. J Exp Clin Cance...