6047 Accesses 22 Citations 2 Altmetric Explore all metrics Abstract Inflammation contributes to the pathogenesis of liver disease, and inflammasome activation has been identified as a major contributor to the amplification of liver inflammation. Transforming growth factor-beta (TGF-β) is a key regulato...
此细胞系表达前列腺特异抗原。二羟基睾丸脂酮轻微刺激细胞生长,经westernblot检测溶解产物与抗雄性激素受体抗体起免疫反应。EGF刺激细胞生长,但TGFβ-1不能抑制细胞生长。该细胞在裸鼠中成瘤。 NCI-H520[H520]细胞系;细胞传代方法:1:2-1:3传代;每周换液2-3次;细胞形态特性:详见细胞说明书;细胞生长特性:贴壁或...
Hypoxia induces the activation of human hepatic stellate cells LX-2 through TGF-beta signaling pathway. FEBS Lett 2007;581:203-210.Hypoxia induces the activation of human hepatic stellate cells LX-2 through TGF-beta signaling pathway. Shi YF,Fong CC,Zhang Q, et al. FEBS Letters . 2007...
结论1)RHL可能是通过抑制TGF-β1/Smads信号通路的传导,达到抗纤维化的作用。2)RHL可能是通过促进LX-2人肝星形细胞系的凋亡,达到抑制LX-2人肝星形细胞系增殖的作用。3)RHL可能是通过抑制TGF-β1/Smads信号通路转导,达到抑制HSC细胞活化的作用。 参考文献 [1]Transforming growth factor beta signaling in hepatocyte...
目的 探讨新城疫病毒(NDV)在活化肝星状细胞(HSC)中的复制情况.方法 用转化生长因子β1(TGF-β1)刺激人肝星状细胞LX-2,MTT法检测细胞的增殖率,RT-PCR检测活化相关基因的mRNA表达.用NDFLtag-EGFP感染不同传代的LX-2细胞和原代分离培养以及TGF-β1刺激活化的HSC,荧光显微镜观察NDV在细胞中的复制.用流式细胞术(...
TGF-β1-stimulated human hepatic stellate LX-2 cells were used as a liver fibrosis model in vitro. The expression of liver fibrogenic genes and signaling proteins in the PI3K/Akt/Smad pathway was examined using Western blotting and/or real-time PCR. Results: In BDL rats, EGCG treatment ...
原价:¥2,384.90 +- 大包装询价添加到收藏夹比较SDS中文版DATASHEET 查看相关系列 Cell Cycle/DNA Damage (2603)Compound libraries (12345)Cytoskeleton (499)ROCK (71)Stem Cell/Wnt (1015)TGF-beta/Smad (303) Skip to the end of the images gallery ...
小鼠脂氧素A4(LXA4)elisa试剂盒转移生长因子β3抗体(TGFβ3) 英文缩写: TGF beta 3 propeptide 转移生长因子β受体2抗体(TGF-βRⅡ,TGFβRⅡ) 英文缩写: TGF beta Receptor II 转移生长因子β受体1抗体 英文缩写: TGF beta Receptor I 甲状腺过氧化物酶抗体 英文缩写: Thyroid peroxidase 受体1相关死亡域蛋白...
产品活性:LX7101是高效的LIMK和ROCK2抑制剂,对LIMK1/2, ROCK, PKA的IC50分别为24,1.6,10,和小于1 nM。 研究领域:Cell Cycle/DNA Damage | Stem Cell/Wnt | Cytoskeleton | TGF-beta/Smad 作用靶点:ROCK In Vitro: LX7101 is a dual LIM-kinase and ROCK inhibitor for the treatment of ocular hypertens...
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