Are new targeted therapies on the horizon? Lupus– epidemiology, symptoms, and current treatments Systemic lupus erythematosus (SLE), commonly referred to as lupus, is a devastating autoimmune disease affecting around 3.41 million people globally. It disproportionately affects women, with approximately 3....
Lupus and antiphospholipid syndrome diagnosis in a young female presenting with multiple non-specific symptomsANTIPHOSPHOLIPID syndromeLEUKOCYTE countFATIGUE (Physiology)ANTINUCLEAR factorsJOINT painDIAGNOSISA female in her 30s with no known past medical conditions presented to North Shore University Hospital ...
Systemic lupus erythematosus(SLE) is an immune-associated collagen vascular disease affecting adolescents and young adults, particularly females. Major clinical manifestations include arthralgia, serositis, abnormal renal functions, and neurologic symptoms. Generalized lymphadenopathy is present in about 12% o...
It is primarily a disease of women, occurring five to ten times more often in females than in males. Although the peak incidence is between 30 and 40 years of age, the condition has also been diagnosed in the very young and the very old.SLE is the classic prototype of autoimmune disease...
Sometimes, symptoms of lupus can be triggered or aggravated by only a brief period of sun exposure. It also is known that some women with systemic lupus erythematosus can experience worsening of their symptoms before their menstrual periods. This phenomenon, together with the female predominance of...
Lupus Systemic Lupus Erythematosus Chronic inflammation of connective tissue which can involve the joints, kidneys, serous surfaces and vessel walls. It occurs predominately in young women but also effects children. Macule or papules may appear and can be round, irregular or butterfly shaped. The ...
Learn more from epocrates about Systemic lupus erythematosus, including symptoms, causes, differential diagnosis, and treatment options
SLE tends to affect young women predominantly, and signs and symptoms can be relatively nonspecific in the initial stages of the disease. Fever, malaise, arthritis, weight loss, and fatigue are often noted, as well as a characteristic erythematous patch that involves the malar skin and bridge of...
These symptoms can arrive in any order at any time, and cause a severe loss of quality of life and reduction in life expectancy. As lupus mostly affects young adult women, the impact of this is great. Why does this happen? We are much closer now to being able to answer this question,...
Analysis of cumulative clinical symptoms showed that butterfly rash (P < 0.05) and livedo reticularis (P < 0.05) were less frequent in the elderly. However, this group presented a significantly increased incidence of sicca syndrome (P < 0.005) and cardiomyopathy (P < 0.005). Antibodies to ...