Lupus nephritisOutcomeTargeted therapiesTreatmentThe aim of this study is to report major recent progresses in the treatment of lupus nephritis (LN). Results of controlled randomized trials are discussed in view of the unmet needs in the field. Current treatments of LN are not satisfactory, with ...
The new treatment, published in the Journal of Clinical Investigation, inhibits specific immune cells associated with lupus nephritis. These T-cells affect the kidney by interacting and binding with other cells, much like a key inserts into a lock. To disrupt the damaging process, the researchers ...
Lupus nephritis is a severe manifestation of systemic lupus erythematosus and a major cause of both acute kidney injury and end-stage renal disease. Preventing, or delaying progression of lupus nephritis is the primary objective of treatment. New treatme
This article first reviews the current treatment of lupus nephritis, with a focus on the most serious forms, that is, the proliferative subtypes. Current standards for treatment have been developed empirically. Corticosteroids form the basis of all regimens. Cyclophosphamide given intravenously for prolo...
The revised International Society of Nephrology/Renal Pathology Society 2003 classification defines the subclasses of lupus nephritis (LN) according to their pathological glomerular patterns, which has a crucial impact on the prognosis and treatment options for LN patients. There are widely accepted ...
Lupus nephritis (LN) is the most common form of kidney disease in ... SV Parikh,LA Hebert,BH Rovin - Springer New York 被引量: 1发表: 2014年 [Lupus-nephritis--diagnosis and treatment] Systemic lupus erythematosus (SLE) is an autoimmune, multiorgan disease that usually affects young women...
To evaluate the safety and efficacy of mycophenolate mofetil (MMF) treatment in patients with lupus nephritis. Eighteen patients with biopsy-proven lupus nephritis (17 females, one male; mean age 31.6 yr; mean lupus duration 92 months; mean duration of nephritis 57 months; nine with focal prolif...
New and more conservative approaches in treatment are a major advance F or 30 years the US National Institutes of Health have dominated the treatment of lupus nephritis with controlled trials of monthly high dose intravenous pulse cyclophosphamide, now the standard treatment for nephritis and severe ...
The treatment of lupus nephritis often consists of a period of intensive immunosuppressive therapy (induction therapy) followed by a period of less intensive maintenance therapy. The established treatment of lupus nephritis with cyclophosphamide and steroids has improved the outcome of LN but is burdened...
Lupus nephritis This is inflammation of the kidneys due to SLE. If the damage is severe, you could needdialysisor a kidney transplant. Cutaneous lupus With this,your faulty immune response causes skin rashes or lesions. There are three types of cutaneous lupus: ...