Effects of rituximab-based B-cell depletion therapy on skin manifestations of lupus erythematosus - report of 17 cases and review of the literature. Lupus. 2013;22:932-9.Hofmann SC, Leandro MJ, Morris SD, Isenberg DA (2013) Effects of rituximab-based B-cell depletion therapy on skin man- ...
Hydroxychloroquine (Plaquenil).This medicine helps control mild lupus-related problems, such as skin and joint disease. It can also prevent symptom flares. Because of potential side effects, you should have regular eye checkups if taking antimalarial drugs for lupus. ...
We investigated the effects of cyclosporin A (CyA) on the development of lupus dermatoses in autoimmune-prone MRL/Mp-lpr/lpr (MRL/lpr) mice. The MRL/lpr mouse is an animal model for the spontaneous development of skin lesions similar to those of human lupus erythematosus (LE). Virgin ...
In the most common form of the disease -- called systemic lupus erythematosus (SLE) -- the immune system mistakenly produces antibodies against the body's own tissue. The onslaught can have widespread effects, damaging the skin, joints, heart, lungs and kidneys. Up to 60% of...
Reiss, A. B. Effects of inflammation on cholesterol metabolism: Impact on systemic lupus erythematosus.Curr. Rheumatol. Rep., 255–260 (2009). PubMed Feichtinger, R. G., Sperl, W., Bauer, J. W. & Kofler, B. Mitochondrial dysfunction: A neglected component of skin diseases., 607–614 ...
LUPKYNIS® (voclosporin) can cause serious side effects, including: Increased risk of cancer. People who take LUPKYNIS have an increased risk of getting some kinds of cancer, including skin and lymph gland cancer (lymphoma). Limit and avoid exposure to sunlight and UV light such as tanning...
Thomas TJ, Messner RP. Effects of lupus-inducing drugs on the B to Z transition of synthetic DNA. Arthritis and Rheumatism 29: 638–645, 1986 Totoritis MC, Rubin RL. Drug-induced lupus. Genetic, clinical and laboratory features. Postgraduate Medicine 78: 149–161, 1985 ...
In another study evaluating the effects of UV irradiation in patients with DLE and SCLE versus normal controls, the authors established that UV exposure of DLE and SCLE skin resulted in enhanced protein degradation and antigen presentation activated by IFNs and that a significant number of IFN-...
Treatment with cyclosporin inhibited the development of glomerulonephritis, distinguishing the effects of IL-6 on systemic inflammation from its direct effect on renal mesangial cells [7]. More impressive were the significant decreases in mortality, progression of proteinuria, and anti-dsDNA antibody ...
A. Effects of rituximab-based B-cell depletion therapy on skin manifestations of lupus erythematosus—report of 17 cases and review of the literature. Lupus 22, 932–939 (2013). CAS PubMed PubMed Central Google Scholar Berghen, N., Vulsteke, J.-B., Westhovens, R., Lenaerts, J. & ...