Background: small cell lung cancer (SCLC) is a leading cause of death all over the world. Diagnostic and therapeutic arsenals have improved in recent years, but we are unsure as to whether these advances have been transferred to clinical practice. The aim of this study was to evaluate ...
We also investigated the top features associated with prognosis in lung adenocarcinoma and squamous cell carcinoma. In the adenocarcinoma group, the primary prognostic features that distinguished longer-term survivor from shorter-term survivors included Zernike shape features of the nuclei and cytoplasm and...
Immunohistochemical algorithm for differentiation oflung adenocarcinoma and squamous cell carcinoma based on large series ofwhole-tissue sections with validation in small specimens. Mod Pathol, 2011,24(10): 1348-1359. [4] NONAKAD. A study of DeltaNp63 expression in lung non-small cell carcinomas....
Small cell lung cancer (SCLC) is one of the two major types of lung cancer. It is named because the cells appear small and round under the microscope. Facts You Should Know About Small-Cell Lung Cancer When cells of the lung start to undergo a degenerative transformation in appearance and ...
Oat-cell carcinoma of the lung. Its origin and relationship to bronchial carcinoid. Cancer 22, 1163–1172 (1968). CAS PubMed Google Scholar Pearse, A. G. 5-Hydroxytryptophan uptake by dog thyroid 'C' cells, and its possible significance in polypeptide hormone production. Nature 211, 598–...
Meanwhile, SCLC is responsible for approximately 93% of all high-grade neuroendocrine carcinomas. These properties contribute to an exceedingly dismal prognosis of SCLC, with a 5-year survival rate of less than 5% [3]. Over the last two decades, frontline therapeutic choices have remained ...
Small-cell carcinoma (also called oat cell cancer) Combined small-cell carcinoma They’re named for the kinds of cells found in each cancer and what they look like. Small-Cell Lung Cancer Causes Smoking is a cause of most lung cancers. Small-cell lung cancer is diagnosed most often in hea...
SCCs with prominent peripheral palisading of nuclei at the edge of tumor cell nests are called the basaloid variant of SCC (Fig. 26.12). The basaloid carcinoma (pure) and the (mixed) basaloid variant of lung SCC have a dismal prognosis, but their underlying specific molecular charac...
Small-Cell Lung Cancer Prognosis The success of treatment depends on the stage of small-cell lung cancer. Unfortunately, in most people with small-cell lung cancer, the disease has already spread to other organs of the body by the time it is diagnosed. That shortens life expectancy. ...
prognosis of those with advanced disease, such as stage IIIB or stage IV, is poor and less than 5% [3]. Only about 15% of patients are diagnosed with early-stage disease, and most (84%) are in an advanced stage at the time of diagnosis. Altogether, Non-small cell lung cancer (...