After returning to the stage and falling deeply in love with a then-unknown Meryl Streep, Cazale received a terminal prognosis of bone cancer, which almost jeopardized him being cast in Michael Cimino's "The Deer Hunter" (1978). Cazale's scenes were filmed quickly and died before the film...
4.2. 'Shotgun' Cloning of Prepropeptide Encoding cDNAs An aliquot of 5 mg of lyophilised skin secretions were dissolved in 1 mL of lysis/binding buffer (Life Technologies, Oslo, Norway). Magnetic oligo-dT Dynabeads (Life Technologies) were applied to isolate mRNAs based on A-T pairing ...
Tragically, the somber reality of this disease is further emphasized by the projected 1.8 million deaths it is expected to cause within the same year, cementing its place as the leading cause of cancer-related fatalities on a global scale. While lung cancer rates and statistics may vary across...
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2.9. FLICA Staining HMVEC-L (1.1 million cells) were plated on a 96-well plate in EGM media and incubated with serum-derived EV (v/v ratio 1:00) from control and TBI patients for 4 h at 37 ◦C. During the last hour of incubation, cells were labeled with carboxyfluorescein (FAM)-...
TRPV3 might serve as a potential companion drug target in NSCLC. Keywords: non-small cell lung cancer; TRPV3; proliferation; [Ca2+]i; cell cycle 1. Introduction Lung cancer is the world's leading cause of cancer death [1]. There are two main types of lung cancer: non-small cell lung...
Claudins are integral membrane proteins of TJs and comprise a large family of 27 subtypes in a mammal [4,5]. Dysregulation of claudins expression has been shown in various tumor tissues [6]. We have been reported that the expression of claudin-2 is up-regulated in human lung adenocarcinoma ...
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