"Interstitial lung disease" refers to a broad group of diseases that are characterized by lung scarring, including idiopathic lung fibrosis. This scarring makes it difficult to breathe and get oxygen into the bloodstream. Lung damage from this group of diseases may be irreversible and get worse ...
Objective: The objective of this research was to determine the impact of glucocorticoid treatment on preventing scarring of lung parenchyma in COVID-19 patients by considering their health behavior. Methods: A sample of 65 Turkish patients who had pneumonia and were hospitalized between March/...
but doctors have struggled to visualize this damage. Conventional chest scans do not reliably detect signs oflungscarring and other pulmonary abnormalities, which makes it difficult to track the health and recovery of people with persistent breathing problems and other post-COVID complications. ...
Idiopathic pulmonary fibrosis (IPF) is the most common and severe type of interstitial lung disease (ILD) characterized by dysregulated alveolar repair leading to pathological lung scarring [178,179]. IPF physiopathology relies on repeated lung micro-injuries leading to DNA damage and cell death tri...
Reduced total lung capacity, vital capacity, or resting lung volume result from diseases affecting the lung tissue, i.e., parenchymal lung disease, such as scarring of lung tissue, or to general or localized disease processes in the lung tissue, e.g., sarcoidosis, fibrosis, or other ...
Chemotherapyand radiation therapy can trigger a cough. So might inflammation or scarring from lung cancer surgery. But you can have a cough for reasons other than lung cancer or its treatment. Causes of chronic cough Common causes of chronic cough include: ...
Interstitial lung disease is a group of respiratory disorders affecting the tissue around the alveoli of the lungs with progressive scarring. Symptoms most commonly begin with a cough, but can progress to chest tightness, shortness of breath, fatigue, and weight loss. ...
Fibrotic scarring follows severe respiratory infections Fibroblasts reside in the lung interstitium at low frequency. In response to injury, fibroblasts are activated, leading to an increase in their numbers. Fibroblast activation, which is thought to promote tissue repair, is typically driven by signal...
It is characterized by the scarring of lung tissue and the accumulation of extracellular matrix (ECM) components that lead to pulmonary dysfunction and failure1. LF in patients is currently incurable, however treatment with (1) the tyrosine kinase inhibitor Nintedanib and (2) the pyridone ...
ILD is a broad term to describe conditions that cause progressive scarring (fibrosis) of the lungs. This hampers lung functioning that worsens with time. ILD occurs due to a combination of genetic and environmental factors, such as hazardous chemicals, cigarette smoke, and asbestos. When this oc...