Here, we compared the level of inflammation in the wall of the tuberculoma and in the parenchymal lung tissue of 30 patients diagnosed with tuberculoma without a history of COVID-19 and 30 patients diagnosed with tuberculoma 3 months after COVID-19. We also characterized TB activity...
which are produced by immune cells in excessive numbers during lung inflammation, preventing full restoration of lung structure and function. In such cases, healthy stem and progenitor cells might have to be transplanted into a person's lungs. However, as with any transplant, immune rejection is ...
Scientists have revealed that protracted inflammation following COVID-19 is strongly linked to long-term changes in lung structure and function, according to a report published today ineLife. The results suggest that monitoring people for markers of inflammation after infection with the SARS-CoV-2 vi...
and adults diagnosed with SARS-CoV-2 infections by RT-PCR at Princes of Wales hospital in Hong Kong were assessed for study eligibility. Patients with immunosuppressant treatment, pregnancy/lactation, end-stage renal failure
abnormalities in COVID-19. We have identified dysregulated genes related to respiratory and lung-related processes upon the SARS-CoV-2-infection. We have prioritized these pathways and searched for potential therapies/drugs for the treatment which could lessen the resultant effects of gene ...
Here, we propose for the first time that IL-37, by blocking IL-1, may have an important role in the therapy of COVID-19. 展开 关键词: COVID-19 IL-1 IL-6 SARS-CoV-2 immunity lung inflammation macrophages and mast cells DOI: 10.23812/20-1-E ...
Although infection initiates in the proximal airways, severe and sometimes fatal symptoms of the disease are caused by infection of the alveolar type 2 (AT2) cells of the distal lung and associated inflammation. In this study, we develop primary human lung epithelial infection models to understand...
Montefiore Health System and Albert Einstein College of Medicine are the first sites in the nation to begin evaluating an investigational drug in two separate, FDA-approved trials: one to treat mild-to-moderate cases of COVID-19 and the other to treat se
Cannabidiol, or CBD, may help reduce the cytokine storm and excessive lung inflammation that is killing many patients with COVID-19, researchers say. While more work, includingclinical trialsto determine optimal dosage and timing, is needed before CBD becomes part of the treatment for COVID-19,...
Serine-Protease (TMPRSS) gene family which prime the virus spike protein for cell entry. Other genes from the gene-signature are associated with reduced immune responses and activated inflammation, Reactive Oxygen Species (ROS) and cellular stress. Credit: WruckW /AdjayeJ, HHU Duesseld...