Restrictive lung disease (e.g., allergic alveolitis, asbestosis, collagen vascular disease, desquamative interstitial fibrosis, eosinophilic granuloma, idiopathic pulmonary fibrosis, post-chemotherapy, sarcoidosis, and systemic sclerosis [scleroderma]): For persons with sarcoidosis, see the disease-specific...
This study aimed to estimate the current prevalence, incidence, and mortality of F-ILD classified as idiopathic pulmonary fibrosis (IPF), PF-ILD other than IPF, and non-progressive F-ILD and their temporal trend in Korea.MethodsPopulation-based retrospective cohort study was conducted using the ...
of the total cost. Owing to the financial problems associated with rare intractable diseases, the ICD for these diseases has high sensitivity and specificity30. The ICD-10 code C34 was used for malignant neoplasms of the bronchus and lung. To estimate the cumulative incidence of LC in patients...
ICD: International classification of disease ILD: Interstitial lung disease IPF: Idiopathic pulmonary fibrosis NCC: National cancer center NHI: National health insurance RA: Rheumatoid arthritis References Gochuico BR, Avila NA, Chow CK, Novero LJ, Wu HP, Ren P, MacDonald SD, Travis WD...
Consistent with our ConsensusPathDB findings, Ingenuity Pathway Analysis (https://digitalinsights.qiagen.com/IPA)39 highlighted enrichment of cardiac hypertrophy signaling and osteoarthritis pathways and also implicated pulmonary and hepatic fibrosis signaling pathways, axonal guidance and PTEN signaling as ...
Cystic fibrosis 5 (1) 2 (1) 3 (3) 0.042 Sarcoidosis 2 (0.4) 2 (1) 0 (0) 0.449 Comorbidities Diabetes mellitus 22 (4) 16 (4) 6 (5) 0.874 Chronic heart failure 27 (5) 21 (5) 6 (5) 0.985 Hypertension 6 (1) 4 (1) 2 (2) 0.517 Abbreviations: CLT, cadaveric lung transpl...
“undefined fibrosis”. The diagnosis was confirmed by histology in 63% of the cases. The overall male-female ratio was nearly one, with, however, a male preponderance in hypersensitivity pneumonitis (22/12), UIP(8/3) and “undefined fibrosis” (14/7). All age groups were represented but...
inflammatory reaction of pulmonary parenchyma that causes irreversible fibrosis and scarring, accompanied by an impaired immune response [20–22]. Chronic TB infections cause the accumulation of genomic changes, and exposure to growth factors can cause multistep cellular transformation, leading to ...
(e.g. nodules, fibrosis, emphysema) suggesting that the model identifies anatomical changes known to be correlated with increased risk. Second, the majority of participants in all datasets (development and testing) were Non-Hispanic White. Detailed analysis regarding generalizability of the model to ...
(rs12610495:G > A) was associated with decreased risk of idiopathic pulmonary fibrosis (IPF)32where the same allele confers the protection against COVID-19 severity. Interestingly, we found the opposite direction of effects between IPF and COVID-19 in the sQTL forATP11A, where the rs...