lung cancernon–small cell lung carcinomaimmunohistochemistrypredictive biomarkerPD-L1antibody-drug conjugatesImmunohistochemical (IHC) staining represents a comparatively inexpensive testing method that is attractive as a potential alternative to molecular sequencing methods or fluorescence in situ hybridization for...
The oncogenic role of PKCiota gene amplification and overexpression in Chinese non-small cell lung cancer (2013) Immunohistochemistry evaluation of biomarker expression in non-small cell lung cancer (Pharmacogenoscan study) . Lung Cancer . doi: 10.1016/j.lung... Qingquan,Luo,Lili,... - 《Lung...
Immunohistochemistry in the Differential Diagnostics of Primary Lung CancerAn Investigation Within the Southern Swedish Lung Cancer Study Immunohistochemistry in the differential diagnostics of primary lung cancer: an investigation within the Southern Swedish Lung Cancer Study. Am J Clin Pathol ... H ...
BACKGROUND: It has been drawn much attention to identify the molecular markers by immunohistochemistry (IHC) for evaluating the prognosis of non-small cell lung cancer (NSCLC) following resection. The aim of this study is to retrospectively associate ever tested IHC markers and prognosis of NSCLC ...
To solve this matter in future experiments, we will investigate cancer promoting cytokines/chemokines and specific immune cell markers. Our results emphasize the direct implication of BMDCs in lung epithelial tumor development. Further studies are warranted to dissect the mechanisms that regulate BMDCs’...
(Fig.8e). Because an RNA-seq database for lung cancer brain metastasis is currently unavailable, we tested the TME network markers with a cohort of low-grade glioma (LGG,n = 515, TCGA), which has been shown recently to share many common TME features with BrMs16. We found that ...
97 However, there is no blood-based marker for immunotherapy available and all information about blood-based markers are exploratory in nature. As mentioned previously, immune checkpoint inhibition has emerged as a novel and promising therapeutic option in the treatment of lung cancer. However, some...
Metastasis is the primary cause of mortality in small cell lung cancer (SCLC), with the liver being a predominant site for distal metastasis. Despite this clinical significance, mechanisms underlying the interaction between SCLC and liver microenvironment, fostering metastasis, remain unclear. ...
et al. Immunohistochemistry in the differential diagnostics of primary lung cancer: an investigation within the Southern Swedish Lung Cancer study. Am. J. Clin. Pathol. 140, 37–46 (2013). Article PubMed Google Scholar Yanagisawa, K. et al. Proteomic patterns of tumour subsets in non-small...
Based on single-cell expression levels of genes commonly used as markers for immunohistochemistry-based NSCLC classification, namely NAPSA, TTF-1 (NKX2-1) for lung adenocarcinoma (LUAD), and TP63, CK5 (KRT5) for lung squamous carcinoma (LUSC), subtype classifications aligned well with the histo...