Hereditary factors in multiple primary malignancies associated with lung cancer. Surg Today. 2007; 37 :375–378. doi: 10.1007/s00595-006-3420-5. [ Cross Ref ]Haraguchi S, Koizumi K, Hioki M, Hisayoshi T, Hirata
Hereditary lung cancer syndrome targets never smokers with germline EGFR gene T790M mutations. J Thorac Oncol 2014;9:456-463.Gazdar A, Robinson L, Oliver D, et al. Hereditary lung cancer syndrome targets never smokers with germline EGFR gene T790M mutations. J Thorac Oncol. 2014;9(4):456...
Lung cancer is a leading cause of cancer death in the U.S. and worldwide and represents a major public health problem1. Hereditary factors play a crucial role in lung cancer pathogenesis2. The first wave of genome-wide association studies3identified susceptibility regions and common variants for...
(2). This mutation is caused by environmental or hereditary reasons, but doctors usually are not able to identify the exact cause (4). However, it is important to examine a cancerous cell under a microscope because that helps the doctors identify the type of lungcancer, so they can give ...
lung cancer was associated with a twofold increased lung cancer risk; this was even greater when the first-degree relative was diagnosed at a young age and/or in individuals with multiple affected family members152. A subsequent study of epidemiological risk factors in people who had never smoked...
First discovered in the mid-1980s, the hepatocyte growth factor receptor (MET) pathway was found in the 1990s to be dysregulated in lung cancer (Fig. 1A).5, 6 More than 20 agents targeting MET or its ligand, hepatocyte growth factor (HGF), have undergone preclinical and clinical study, ...
Lung cancer: Lung cancer is a type of cancer that attacks the healthy tissue of the lungs of the patient. Inhalation of radon gas has been linked with the onset of the disease. Answer and Explanation:1 A multitude of factors will indicate that the cancer in the lung is inoperable. These...
Some advice that is given to a patient to address the risk factors of lung cancer are: Quit smoking: Smoking is responsible for producing nearly 90%...Become a member and unlock all Study Answers Start today. Try it now Create an account Ask a question Our experts ...
industrial toxins and exhaust pollution are also risk factors for the development of lung cancer (de Sousa and Carvalho2018; Raman et al.2022). It is evident that it is extremely urgent to overcome the challenge of lung cancer treatment technology. Like most tumors, lung cancer consists of ...
Pathogenic genetic variants (formerly called mutations) present in the germline of some individuals are associated with a clinically relevant increased risk of developing lung cancer. These germli