LUNESTA is a CNS depressant and can impair daytime function in some patients at the higher doses (2 mg or 3 mg), even when used as prescribed. Prescribers should monitor for excess depressant effects, but impairment can occur in the absence of symptoms (or even with subjective improvement)...
CNS Depressant Effects and Next-Day Impairment LUNESTA® is a CNS depressant and can impair daytime function in some patients at the higher doses (2 mg or 3 mg), even when used as prescribed. Prescribers should monitor for excess depressant effects, but impairment can occur in the absence...
Effect Of Food In healthy adults, administration of a 3 mg dose of eszopiclone after a high-fat meal resulted in no change in AUC, a reduction in mean Cmax of 21%, and delayed tmax by approximately 1 hour. The half-life remained unchanged, approximately 6 hours. The effects of LUNESTA ...
However, this maximum recommendation from the manufacturer for the daily dose using Lunesta must not exceed 3 mg in each case. Therefore to avoid untoward effects and tolerance, it is vital to follow the dosage instructions of your doctor accurately....
Nonbenzodiazepine Hypnotic Agentfor common effects Metallic Taste Reported in up to 34% of patients on 3 mg Very bothersome - discontinuation is common Amnesia Hallucinations Worsening depression VIII. Advantages SeeNonbenzodiazepine Hypnotic Agent
Three nursing women (time postpartum not stated) received a single oral dose of zopiclone 7.5 mg. Peak milk levels of about 55 mcg/L occurred about 2 hours after the dose. The half-life in milk was similar to that in plasma which was 5.3 hours in healthy adults.[3,4] Twelve nursing...