2729 Objectives Lu-177-DOTA-Octreotate, a mixed beta and gamma emitter, is a new therapeutic radiopharmaceutical used to treat neuroendocrine tumors. In this study, the gamma energy spectrum, counting efficiency, lower level of detection (LLD) and trigger levels for Lu-177 were obtained on ...
177Lu energy spectrum acquired with the hand-held camera. Photopeak energy windows are indicated in grey, and lower and upper scatter-energy windows in blue Full size image A resealable phantom was constructed in PMMA, consisting of a cylindrical cavity (20 mm inner diameter and 8 mm height)...
骨转移的吸收剂量与Kulkarni等人报告的177Lu-PSMA-617相似[177Lu-FAP-2286为3.0 Gy/GBq (0.5-10.6 Gy/GBq),177Lu-PSMA-617为2. 9 Gy/GBq],略低于Violet等人报告的177Lu-PSMA-617 [5.3 Gy/GBq (0.4-10.7 Gy/GBq)],尽管其...
The γ-ray spectrum of 177Lu following the β-decay of 1.9 h 177Yb has been studied with Ge(Li) detectors. Investigation of the singles spectrum with a high-resolution 44 cm 3 coaxial Ge(Li) detector revealed twenty-two transitions belonging to the β-decay of 177Yb. Seven of these, ...
In particular, such energy tails produce effects that need to be considered when imaging radionuclides with multiple emissions such as 177Lu. Monte Carlo simulation can be used to investigate the behaviour of such systems and optimise their use, provided that the detector model closely reflects the...
In particular, such energy tails produce effects that need to be considered when imaging radionuclides with multiple emissions such as 177Lu. Monte Carlo simulation can be used to investigate the behaviour of such systems and optimise their use, provided that the detector model closely reflects the...
The beta-decay of Lu177 has been investigated and four beta-groups of maximum energies 496.8±1.7, 385±2, 249±4 and 174±3 keV were found. The relative intensities were determined as 90±4, 2.95±0.05, 0.31±0.06 and 6.72±0.25%, respectively. Beta-gamma coincidences have been recorded...
It is remarkably similar in both chemical properties and half-life Lu-177: 6.64 days; Tb-161: 6.95 days, as well as main beta-radiation energy Lu-177: 134 keV; Tb-161: 154 keV) and similar specific activities (Lu-177: max 4.109 PBq/g; Tb-161: max 4.356 PBq/g)....
Background Bone marrow (BM) is the dominant dose-limiting organ in [177Lu]Lu-PSMA-617 therapy for patients with metastasized castration resistant prostate cancer, where BM dosimetry is challenging d...
Camera sensitivity (based on reconstructed SPECT count rate) and dead-time (based on wide-energy spectrum count rate) were resolved by non-linear curve fit. Utilizing these parameters, a SPECT dataset can be converted to a QSPECT dataset allowing quantitation in Becquerels per cubic centimetre ...