一个可能的假设是LTD和LTP可能由不同的神经调质受体通路诱导，这种情况下，potentiantion 和 depression甚...
This raises the question of whether specific mechanisms exist to prevent unwanted interference between the two processes.doi:10.1038/nrn2123Katherine WhalleyNature Reviews Neuroscience
processofLTPandLTD. Keywords:AMAPR;GluA1;GluA2;LTP;LTD 0引言30 哺乳动物中枢系统的连接非常复杂,数十亿个神经元之间进行着高度专业化的信号传递 和处理,突触构成的神经元之间的基本和高阶信息处理构成了正常的大脑功能。其中,AMPA 受体(AMPARs)作为最主要的谷氨酸离子型受体之一,在哺乳动物大脑调节快速兴奋性突...
Neural activity can induce persistent strengthening or weakening of synapses, known as long-term potentiation (LTP) or long-term depression (LTD), respectively. As potential cellular mechanisms underlying learning and memory, LTP and LTD are generally regarded as synapse-specific "imprints'' of activi...
Sadegh Nabavi and Rocky Fox: These authors contributed equally to this work. Authors and Affiliations Department of Neuroscience and Section of Neurobiology, Center for Neural Circuits and Behavior, University of California at San Diego, 92093, California, USA Sadegh Nabavi, Rocky Fox, Christophe D....
Learning and memory Neuroscience This article is cited by The phase of plasticity-induced neurochemical changes of high-frequency repetitive transcranial magnetic stimulation are different from visual perceptual learning Shang-Hua N. Lin Yun R. Lien ...
海马LTP/LTD诱导中CaMKⅡ磷酸化水平的变化 长时程增强(LTP)/长时程压抑(LTD)是由强直/低频刺激作用于兴奋性突触传递通路诱发的一种突触传递效率长时间增强/减弱的现象,两者均被认为是很好的研究学习和记忆机制... 殷文娟,祁金顺 - 《山西医药杂志:上半月》 被引量: 0发表: 2009年 CaMKII inactivation by ...
突触后膜内存在着有关LTD的磷酸化酶和有关LTP的激酶。两种酶的作用是同时存在的。至于究竟是产生LTD...
突触后膜内存在着有关LTD的磷酸化酶和有关LTP的激酶。两种酶的作用是同时存在的。至于究竟是产生LTD...
内容提示: Engineering a memory with LTD and LTPSadegh Nabavi 1,* , Rocky Fox 1,* , Christophe D. Proulx 1 , John Y. Lin 2 , Roger Y. Tsien 2,3 , and Roberto Malinow 1,+1 Center for Neural Circuits and Behavior, Department of Neuroscience and Section of Neurobiology, University of...