LRF loss at HSC/progenitor levels led to excessive differentiation of HSCs into T cells in the BM at the expense of B cell development. Concomitantly, the numbers of LT-HSCs (CD34CD150+CD48Flt3IL7R伪LinSca-1+c-Kit+) were significantly reduced in LRFflox/floxMx1-Cre+ mice one month ...
就这样错过了最后的🍓错过了短暂的🌸 错过了初夏的☀️ 五月的天 本来要唱刚诞生的夏天现在只能唱唱囚鸟了🐦[挖鼻] #施沛岑carol[超话]# Tee&马甲&包:Li-Ning x Muppets 裤:NBA 👟:Li-Ning #心动告白季##OOTD[超...
LT-HSCs from AhR-KO mice display alterations in gene expression: LT-HSCs from aged AhR-KO and WT mice were sorted and analyzed for changes in gene expression using qPCR.John, A. BennettKameshwar, P. SinghZeenath, Unni...
The CD150high compartment is not the exclusive reservoir of LT-HSCs within the bone marrow. Blood. 2008; 111 :4414–5.Chambers S.M., Weksberg D.C., Goodell M.A. 2008. Response: The CD150high compartment is not the exclusive reservoir of LT-HSCs within the bone marrow . Blood. 111...
Aging alone changes gene expression in LT-HSCs.John, A. BennettKameshwar, P. SinghZeenath, UnnisaStephen, L. WelleThomas, A. Gasiewicz
The CD150high compartment is not the exclusive reservoir of LT-HSCs within the bone marrow. Blood. 2008; 111 :4414–5.Chambers S.M., Weksberg D.C., Goodell M.A. 2008. Response: The CD150high compartment is not the exclusive reservoir of LT-HSCs within the bone marrow...
Npm1ca Overcomes the Differentiation Block of DNMT3A-Mutant LT-HSCs to Transition MDS to Myeloproliferative Disorderdoi:10.1016/j.exphem.2018.06.165Jennifer TrowbridgeMatthew LobergRebecca BellTim StearnsLeslie GoodwinKira YoungDavid BergstromRebekka Schneider...
Angptl3 augments the expansion of LT-HSCs from LSK cells.Elnaz, FarahbakhshianMonique, M. VerstegenTrudi, P. VisserSima, KheradmandkiaDirk, GeertsShazia, ArshadNoveen, RiazFrank, GrosveldNiek, P. van TilJules, P. P. Meijerink
LT-HSC marker expression is altered on Runx1 deficient HSCs.Xiongwei, Cai
Selected genes related to Hematological System Development and Function found to be altered in LT-HSCs of aged AhR-KO mice.John, A. BennettKameshwar, P. SinghZeenath, UnnisaStephen, L. WelleThomas, A. Gasiewicz