现在，研究人员利用iPSC (诱导多能干细胞)技术建立了关于LQTS type 2（由“钾通道编码基因”KCNH2的一...
Epirubicin-induced QT prolongation, monomorphic ventricular tachycardia and response to beta blockade in LQTS type 2AnthracyclineBeta-blockerCancer therapyCardio-oncologyEpirubicinLQT2Long QTMetoprololPropranololQT interval prolongationdoi:10.1016/j.hrcr.2020.07.005Milos Kesek...
(1) did provide insightful results by focusing their analysis on these LQTS type 1 and LQTS type 2 patients with a QTc interval <460 ms. Their results confirmed that these morphological parameters can complement the QTc interval prolongation in diagnosing LQTS (5), and also one may speculate ...
『团长转业到地方是什么级别?能当县长吗?』https://mp.weixin.qq.com/s?chksm=c19e3dfff6e9b4e97707073d126296140d4bb35c6570da04ce6bd5ae60828331ad1cb0938eea&exptype=unsubscribed_card_recommend_article_u2i_mainprocess_coarse_sort_tlfeeds&ranksessionid=1708169092_1&mid=2247484156&sn=2ad9e982a8e57a...
FUNDING ACKNOWLEDGEMENT. Type of funding sources: Public grant(s) 鈥 National budget only. Main funding source(s): Canadian Institute of Health Researchdoi:10.1093/eurheartj/ehab724.0651L YeeH.C HanB DaviesA KrahnHearts in Rhythm OrganizationEuropean Heart Journal...
Post-operative ECG showed coved type ST elevation in lead V1-4. This finally gradually reverted in ten days after operation and normalized within 2 weeks. Case 2. A 69 year-old male, who had paroxysmal AF and esophageal cancer, received the same procedure as in case 1. His ECG revealed...
calmodulin, L-type calcium channels, long QT syndrome, ryanodine receptor, sodium channelsBackgroundCalmodulin (CaM) is encoded by three genes, CALM1, CALM2, and CALM3, all of which harbor pathogenic variants linked to long QT syndrome (LQTS) with early and severe expressivity. These LQTS-...
We identified a LQTS family harboring three compound mutations in different genes (KCNQ1-R174C,hERG-E1039X andSCN5A-E428K).KCNQ1-R174C,hERG-E1039X andSCN5A-E428K mutations and/or relevant wild-type (WT) cDNAs were respectively expressed in mammalian cells.IKs-like,IKr-like,INa-like ...
Congenital long QT syndrome (LQTS) is a heritable cardiac disease whereby patients are at an increased risk for LQTS-triggered syncope, seizures, and sudden cardiac arrest. Seizure episodes are common in LQTS and most often seen in patients with type 2 LQTS (LQT2).To determine the prevalence ...