DSS induced colitis increases portal LPS levels and enhances hepatic inflammation and fibrogenesis in experimental NASH . J Hepatol 2011; 55 : 1391–1399.Gäbele E, Dostert K, Hofmann C et al. DSS induced colitis increases portal LPS levels and enhances hepatic inflammation and fibrogenesis i...
A colitis-associated CRC mouse model administered three cycles of azoxymethane/dextran sulfate sodium (AOM/DSS) was used to examine the relationship between epithelial cell death and tumor development, and the extent of LPS exposure to gut mucosa during disease progression. First, baseline levels of ...
Lipopolysaccharide (LPS) is found in the outer membrane of many (but not all) gram-negative bacteria, contributing greatly to the structural integrity of the bacteria [4]. LPS mainly comprises three parts: O antigen (or O polysaccharide), core oligosaccharide, and Lipid A [5,6]. Lipid A,...