气道纤维化EMT转化整合素αvβ6铜绿假单胞菌(Pseudomonas aeruginosa,P.aeruginosa)是临床常见的机会致病菌,具有复杂的耐药机制,可引起严重的下呼吸道感染.近年来,由于泛耐药菌株的流行,铜绿假单胞菌下呼吸道感染患者常出现抗感染疗程延长,迁延不愈,甚至导致患者病死率增加.反复感染与气道上皮的纤维化修复密切相关,...
Our other study indicated that SEC or SMC ameliorated H2O2-induced apoptotic, oxidative and inflammatory injury in human BEAS-2B cells (bronchial cells) through preserving Bcl-2 expression, decreasing ROS formation and limiting protein expression of NAPDH oxidase, NF-κB and MAPK [16]. Those ...