The present invention provides novel Gram-negative bacteria polypeptide display A3-O- deacylated lipid activity and can modify and / or gram-negative bacteria detoxify LPS. 本发明还提供革兰氏阴性菌,革兰氏阴性菌脂多糖(LPS)以及包含LPS的组合物,它们具有本发明的3-O-脱酰基酶活性或经过其处理,并且它们...
3. Zhang G,Meredith TC,Kahne D. On the essentiality of lipopolysaccharide to Gram-negative bacteria. Curr Opin Microbiol. 2013;16(6):779–85. doi: 10.1016/j.mib.2013.09.007. PubMed PMID: ; PMCID: PMC3974409. 4. Nikaido H. Molecular basis of bacterial outer membrane permeability revisited....
CAS号: 英文名: Lipopolysaccharide(LpsGramNegativeBacteria) 英文别名: Lipopolysaccharide(LpsGramNegativeBacteria) 中文名: 中文别名: CBNumber: CB31019350 分子式: 分子量: 0 MOL File: Mol file 化学性质 安全信息 用途 供应商 3 Lipopolysaccharide(LpsGramNegativeBacteria)化学性质...
8. Ursell et al. Analysis of Surface Protein Expression Reveals the Growth Pattern of the Gram-Negative Outer Membrane. PLoS Comput Biol., v.8(9); 2012 Sept. PMC3459847` 9. Jaroslawski et al. High-resolution architecture of the outer membrane of Gram-negative bacteria Roseobacter denitrifican...
Grunwald U,Fan XL,Jace RS,et al.Monocyte can phagocytose gram-negative bacteria by a CD14-depedent mechamism.J Immunol 1996,157:4119 Geger JA,Ulevitch RJ,Tobias PS,LPS signal transduction and clearance, J Biol Chem,1995,270(10):5320 ...
3 Inagawa H, Nishizawa T, Yoshioka N, Taniguchi Y, Kohchi C and Soma G: Preventative and therapeutic potential of lipopolysaccharide derived from edible Gram-negative bacteria to various diseases. Curr Drug Ther 3: 26-32, 2008. 4 Kadowaki T, Yasui Y, Takahashi Y, Kohchi C, Soma G and...
3 Inagawa H, Nishizawa T, Yoshioka N, Taniguchi Y, Kohchi C and Soma G: Preventative and therapeutic potential of lipopolysaccharide derived from edible Gram-negative bacteria to various diseases. Curr Drug Ther 3: 26-32,...
Günther等人的文章“'Cytosolic Gram-negative bacteria prevent apoptosis by inhibition of effector caspases through LPS”发表在新一期的《Nature Microbiology》上。志贺氏菌是引起细菌性痢疾——急性炎症性腹泻的病原菌,Kashkar教授的实验室现已证明,志贺氏菌可以通过表明产生的脂多糖有效地以其O抗原结合并阻断某些...
脂多糖是细菌外膜的组成部分,是一种有效的Caspase酶抑制剂。这种策略使细菌能够在细胞内繁殖而不受细胞凋亡的影响。Günther等人的文章“'Cytosolic Gram-negative bacteria prevent apoptosis by inhibition of effector caspases through LPS”发表在新一期的《Nature Microbiology》上。
a process deemed essential for caspase-4 activation. In contrast to GBP1, closely related paralog GBP2 is unable to bind bacteria on its own but requires GBP1 for direct bacterial binding. Unexpectedly, we find that GBP2 overexpression can restore gram-negative-induced pyroptosis in GBP1KOcell...