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The optimization task is to identify simultaneously a plant design and a suitable plant schedule to optimize an economic objective function. MINLP DESS models typically have binary variables representing the facility selection and the operation states of selected units. Continuous variables model input ...
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(A) Timeline depicting administration schedule for minocycline, paeonol and LPS. Mice received i.p. minocycline (40 mg/kg) 1 h prior or i.p. paeonol (100 mg/kg) 20 min prior to LPS (100 µg/kg) administration. At 6 h after LPS administration, the mice were subjected...
(A) Drug (Nec-1 S and LPS) treatment schedule. Immunoblots (right) and bar graphs (left) show the expression and phosphorylation of RIPK1, eIF4E, PI3K, Akt, and mTOR in the N2a Cells (n = 6–8). (B) Drug treatment schedule (left), Quantitative Bar graphs, and immunoblots ...
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Following the designated vaccination schedule, the chickens were immunised and then exposed to the SG WT 422 strain through intramuscular (IM) injection. Body weight measurements and observations for potential mortality were conducted regularly throughout the experiment. Immunisation with detoxified SG stra...
Mice were treated with vehicle, LPS, and osmotin, as described in the drug treatment schedule, to evaluate the memory-improving effect of osmotin (Fig. S4). All animal groups were trained to find the hidden platform in a water pool for 4 days, and the Morris water maze test was perform...
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