Membranes were then incubated under constant agitation with the following primary antibodies: human alkaline phosphatase (ALPL) antibody (Clone 928929, R&D Systems; dilution 0.25 µg/ml), IGSF-1 polyclonal antibody (ThermoFisher Scientific; dilution 1:1000), and beta actin monoclonal antibody ...
Although there have been no documented cases of chylomicronemia directly attributed to natural LPL autoantibodies, laboratory findings have identified a monoclonal antibody, 88B8, that disrupts the binding of LPL to GPIHBP1 [78]. This discovery suggests that there may be unrecognized significance in ...