Several methods are currently used to study the assembly of Lp[a], however, these methods are laborious, time-consuming, and not suitable for a high throughput screening. We report here the development of a rapid and simple assay based on the binding of labeled LDL to a Lp[a]/apo[a] ...
Structure-function relationships in apolipoprotein(a): insights into lipoprotein(a) assembly and pathogenicity. Curr Opin Lipidol. 2004; 15(2):167–174. (Open in a new window)PubMed (Open in a new window)Web of Science ®(Open in a new window)Google Scholar...
Mipomersen had no effect on apolipoprotein(a) levels or hepatic apolipoprotein(a) mRNA expression, so that the mechanism was likely related to preventing assembly of Lp(a) by limiting the amount of apoB-100 available (33). This approach was not ideal as the mice continued to make free ...
We need a new commercialization model for therapeutic development for this new era of “n of one” patient 9:50-10:15 Implementation of a CLIA-based Reverse Phase Protein Array Assay for Precision Oncology Applications: Proteomics and Phosphoproteomics...
Species and assembly/genomic database support:VEP can analyze data from any species with assembled genome sequence and annotated gene set. VEP supports chromosome assemblies such as the latest GRCh38, FASTA, as well as transcripts from RefSeq as well as user-derived sequences ...
Thus, to verify this potential, we further determined the protective efficiency by active immune protection assay in a mouse model. As expected, mice that were vaccinated with purified recombinant LptD (Fig. 4a–c) induced strong antibody responses (Figs 4dand5a) with high specificity (Fig. 4d...
Christian P, Sacco J, Adeli K. Autophagy: emerging roles in lipid homeostasis and metabolic control. Biochim Biophys Acta. 2013;1831(4):819–24.This review highlights the emerging importance of autophagy in lipoprotein assembly, energy regulation and lipid storage via recipricol regulation with insu...
We need a new commercialization model for therapeutic development for this new era of “n of one” patient 9:50-10:15 Implementation of a CLIA-based Reverse Phase Protein Array Assay for Precision Oncology Applications: Proteomics and Phosphoproteomics at the Bedside (CME Eligible) Emanuel Petrico...
(aPKC) and is localized to the apical junction domain for the assembly of TJs[31,39]. The Crumbs complex is formed by the transmembrane protein Crumbs and the cytoplasmic scaffolding proteins such as the homologue ofDrosophilaStardust (Pals1) and Pals-associated tight junction protein (Patj) ...
20110128008 Method And Apparatus For Indicating Battery Cell Status On A Battery Pack Assembly Used During Mechanical Ventilation June, 2011 Carter 20110126837 Exhalation Valve Assembly With Integrated Filter June, 2011 Winter et al. 20110126836 Exhalation Valve Assembly With Selectable Contagious/Non-Conta...