Global DNA methylation was assessed in two groups of women whose plasma vitamin B12 concentration was either deficient (148 pmol/L)(n=128). To correct for the possible effects of RBC folate on DNA methylation, a subset (n= 24) of the vitamin B12 normal subjects were further matched for ...
Compared with women in the highest quartile for second trimester weight gain, those in the lowest quartile had a significantly higher adjusted odds ratio (AOR: 3.98; 95% CI: 1.83, 8.65) for IUGR. Women in the lowest tertile for serum vitamin B12 concentration during each of the three ...
dose of 10,000 g cbl on B12 status in B12 deficient subjects with high (>45.3 nmol/L) and normal (蠄45.3 nmol/L) serum folate. 51 elderly participants (73 ± 2.5y, 49% women) with sB12 Figure 1. Vitamin B12 status before and after treatment depending on folate status. Grant ...
The risk of cervical cancer in relation to serum concentrations of folate, vitamin B12, and homocysteine. Due to its role in the synthesis and repair of DNA, folate may protect against the development of cervical cancer. Prospective data on the possible associa... AJ Alberg,J Selhub,KV Shah...
Dose-Response Association of Maternal Levels of Folate, Vitamin B12, and Homocysteine With Congenital Heart Disease (CHD) Risk in Offspring. Credit:JAMA Network Open(2024). DOI: 10.1001/jamanetworkopen.2024.38747 Pregnant women with either low or excessively high levels of folate in their blood may...
Maternal folate and vitamin B12 deficiency predict poor pregnancy outcome. To improve pregnancy outcomes in rural area of China, we investigate rural women?s folic acid supplementation (FAS) status and the associations between maternal vitamin B status during the first trimester and subsequent adverse ...
What Causes Low Vitamin B12? Most people in the U.S. get adequate amounts of vitamin B12, however, certain conditions can make some people more likely to develop vitamin B12 deficiencies, such as: Being older Pernicious anemia Reduced levels of stomach acidity (hypochlorhydria or achlorhydria...
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Marked Gender Difference in Plasma Total Homocysteine Concentrations in Indian Adults with low Vitamin B12. Context: Plasma total homocysteine (tHcy) is higher in men than women. Objective: To explore the gender differences in tHcy in relation to determinants of one-carbon metabolism in Indian people...
found that both low and high hemoglobin (Hb) concentrations during the second trimester were associated with an increased risk of PTB, SGA, and stillbirth, and that high Hb in the third trimester increased the risk of LBW [37]. Vitamin B12 deficiency has also been associated with LBW and ...