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Specifically, acute treatment with the High 21.08±5.76 low physiological dose of 17b-estradiol increases, whereas the middle physiological and high pharmacological doses 17a-Estradiol Low Medium High 31.44±9.96 25.89±7.39 13.06±6.16 disrupt working memory and reference memory perfor- mance, ...
The supernatants of those neuron cultures were further used as neuron-derived conditioned medium (NCM). Fig. 5 LIPUS increases spine density and irisin secretion via upregulating the Fndc5 level in hippocampal neurons. Primary hippocampal neurons were isolated from C57/BL6 wild-type E17 embryos. A...
Currently, chemotherapy remains the primary treatment modality for TNBC. Doxorubicin (DOX), as an anthracycline drug, demonstrates significant efficacy in the neoadjuvant chemotherapy of TNBC. However, in the advanced stages of treatment, tumor cells often develop multidrug resistance (MDR) to ...
LIPUS exhibits substantial promise as a neuromodulation modality. It has the ability to penetrate the skull and impart neuroprotective and reversible neuromodulatory effects. The capacity for reversible neuromodulation through LIPUS presents a new opportunity for the treatment of individuals in the early ...
RAW264.7 (mouse leukemia cells of monocyte-macrophage) were purchased from the American Type Culture Collection and constantly maintained in high glucose Dulbecco's modified eagle medium (DMEM) (HyClone) with 10% fetal bovine serum (FBS) and 0.5 ml of penicillin/streptomycin solution (#0503; Scien...
However, choosing the proper imaging modality to determine ALN burden is still the major challenge. Regarding the ability to predict a specific number of metastatic ALNs, such as one or two ALNs, the diagnostic performances of PET/CT and MRI exhibited modest predictive values, ranging from 8.7 ...
It is thus difficult to compare the effectiveness of these closed-loop, implanted strategies, but it is probable that the epidural modality would also benefit from similar cadence-control techniques. Physiological effects of controlled stimulation Muscle oxygenation data may explain variations in ...
Volumetric imaging, such as cone-beam computed tomography (CBCT) or megavoltage CT, is being rapidly adopted as a common modality in image guided radiation therapy (IGRT)1,2,3,4. In particular, CBCT mounted on the gantry of a linear accelerator is scanned to improve the target accuracy and...
(WZB) for projects with plans to collect survey data in the second half of 2020. Study investigators agreed to include a set of common questions about COVID-19 vaccine attitudes. This strategy was guided by the need to collect information quickly and cost-effectively using a survey modality (...