The most common toxicities were fever, fatigue, hypotension, nausea/emesis, and myalgia/arthralgia. There were 11 episodes of Grade III toxicity including Grade III hypotension in 7 patients. Because of the significant toxicity and the lack of observed response, the study was discontinued. ...
Symptoms of estrogen excess include nausea, breast tenderness, fluid retention, cervical mucorrhea, and cyclic headaches, whereas estrogen deficiency is suggested by early or midcycle BTB, increased spotting, and hypomenorrhea. Symptoms of progestin excess are increased appetite, depression, fatigue, ...
The most common toxicities observed were fatigue, fever,nausea, and vomiting. Side effects were more frequently noted at the higher starting doses. Indeed, none of the 3patients who were initially treated at 6 × 105 U/m2/d were able to tolerate more than 2 weeks at this dose, largely ...
The following are four examples of heavy metals that are poisonous to living organisms and have incredibly harmful effects on human health: (1) Zn: large amounts of zinc dust or vapor can cause symptoms such as thirst, coughing, pneumonia, bronchitis, easy fatigue, nausea, fever, and chills...
pneumonia, lymphopenia, upper respiratory tract infection, diarrhea, and hypokalemia. Dose reductions occurred in 32% of patients treated with ENHERTU. The most frequent adverse reactions (>2%) associated with dose ...
interruption were neutropenia, anemia, thrombocytopenia, leukopenia, upper respiratory tract infection, fatigue, nausea, and ILD. Dose reductions occurred in 18% of patients treated with ENHERTU. The most frequent adverse reactio...
The most frequent adverse reactions (>2%) associated with dose interruption were neutropenia, anemia, thrombocytopenia, leukopenia, upper respiratory tract infection, fatigue, nausea, and ILD. Dose reductions occurred in 18% of patients treated with ENHERTU. The most frequent adverse reactions (>2%)...
The most common (≥20%) adverse reactions, including laboratory abnormalities, were nausea (76%), decreased white blood cell count (70%), decreased hemoglobin (64%), decreased neutrophil count (64%), decreased lymphocyte count (55...
In this pooled safety population, the most common (≥20%) adverse reactions, including laboratory abnormalities, were nausea (78%), decreased white blood cell count (74%), decreased hemoglobin (68%), decreased neutrophil count (68%), increased aspartate aminotransferase (58%), fatigue (57%),...
pneumonia, lymphopenia, upper respiratory tract infection, diarrhea, and hypokalemia. Dose reductions occurred in 32% of patients treated with ENHERTU. The most frequent adverse reactions (>2%) associated with dose reduction were neutropenia, decreased appetite, fatigue, nausea, and febrile neutropenia...