While these findings are novel and provocative, it is premature to request your pathologist to count the number of crypts or biopsies with low-grade dysplasia just yet. However, these findings, if confirmed by studies utilizing a simpler measure of the extent of low-grade dysplasia, may help ...
Background: It has been suggested that BE pts progress through low (LGD) & high grade dysplasia (HGD) prior to the development of esophageal adenocarcinoma; with HGD pts having the highest risk of cancer. However, it is not known if there are certain clinical, demographic and endoscopic featu...
Anti-phosphorylated histone H3-labeled mitotic counts for the three compartments of the crypts and the total scores for Barrett's esophagus, indefinite for dysplasia, low-grade dysplasia, high-grade dysplasia, and adenocarcinoma were compared using the Mann-Whitney U test. For each compartment, the...
Diverse p53 alterations in ulcerative colitis-associated low-grade dysplasia: full-length gene sequencing in microdissected single crypts. J Pathol. 2003;199:166-175.TsutomuYoshida,TetuoMikami,HiroyukiMitomi,IsaoOkayasu.  Diverse p53 alterations in ulcerative colitis‐associated low‐grade dysplasia:...