Pozzi S, Malferrari G, Biunno I, Samaja M. Low-flow ischemia and hypoxia stimulate apoptosis in perfused hearts independently of reperfusion. Cell Physiol Biochem 2002; 12: 39-46.Pozzi S,Malferrari G,Biunno I,et
HIF-1 is believed to play a critical role in hypoxia/ischemia (H/I) preconditioning protection in neonatal brain. Recently, it has been shown that hydrogen peroxide (H2O2) may contribute to H/I preconditioning in rat primary neurons. We hypothesize that H2O2 produced during H/I preconditioning...
Here we investigated the ischemia responses to acute hypoxia and acidification in developing cardiomyocytes derived from neonatal rat hearts (rN-CM) or human induced pluripotent stem cells. L-type Ca(2+) current (ICa) was measured within 4-7 days in the whole-cell perforated-patch (amphotericin...
Milano G, Corno AF, De Jong JW, von Segesser LK, Samaja M. Tolerance of isolated rat hearts to low-flow ischemia and hypoxia of increasing duration: protective role of down-regulation and ATP dur- ing ischemia. Mol Cell Biochem. 2001;226:141-51....