L. (2016) High and low GABA sensitivity alpha 4 beta 2 delta GABA(A) receptors are expressed in Xenopus laevis oocytes with divergent stoichiometries. Biochem.Pharmacol. 103, 98-108.Hartiadi LY, Ahring PK, Chebib M, Absalom NL. High and low GABA sensitivity α4β2δ GABAA recep- to...
Furthermore, it may be that the small amounts of GABA found in peripheral tissue a re not derived from glutamate through GAD but rather from putrescine (Caron et al. 1988). Metabolism of pGABA is by GABA-T in the liver. Activity of GABA-T in liver is almost as high as in brain. ...
ObjectiveTo compare the mRNA and protein expression levels of γ-aminobutyric acid receptor B2 (GABABR2) in brain regions of male rats with high level aggressive behaviors and low level aggressive behaviors respectively, and provide clues for exploring mechanism of GABA in aggressive behaviors.MethodsW...
Glutamate (GLU) and 纬-aminobutyric acid (GABA) are important amino acid neurotransmitters that, respectively, mediate rapid excitatory and inhibitory neur... AMT Monfared,VS Tiwari,VL Trudeau,... - 《IEEE Photonics Journal》 被引量: 7发表: 2015年 Principles of rapid tryptophan depletion and its...
High-dose alcohol intoxication is commonly associated with impaired inhibition, but the boundary conditions, as well as associated neurocognitive/neuroanatomical changes have remained rather unclear. This study was motivated by the counterintuitive findi
This could explain why low dose, but not high dose MA treatment led to increased striatal levels of 5-HT and GABA in PD mice. As we have reported previously [19], [27], [28], fecal SCFAs (mainly AA, PA, and BA) as the main GM metabolites and neuromodulators have been proven to...
A, P values were significant in men and women (P < .001), older and younger participants (P < .001), urban communities (P < .001), rural communities (P = .004), high-income communities (HICs, P < .001), upper–middle-income communities (UMICs, P <...
In addition, preliminary evidence14 suggests that testosterone has short- and long-term γ-aminobutyric acid (GABA)-ergic properties, and these actions may further contribute to the modulation of mood in men. Pope et al15 found that 8 of 50 men aged 20 to 50 years treated with high doses...
Functional mapping of rodent and human islets containing proportionally more PDX1HIGH and MAFAHIGHβ-cells reveals defects in metabolism, ionic fluxes and insulin secretion. At the transcriptomic level, the presence of increased numbers of PDX1HIGH and MAFAHIGHβ-cells leads to dysregulation of gene...
Effect of local activation of GABAergic neurons in the cerebral cortex on EEG power spectrum and sleep amounts Viral delivery of AAV2/5-Syn-FLEX-rc[ChrimsonR-tdTomato] was targeted into the cerebral cortex at the depth of 0.8 mm, so the virus was concentrated in the deep layers of the...