et al. Obstructive sleep apnea is associated with low GABA and high glutamate in the insular cortex. Journal of sleep research, doi: 10.1111/jsr.12392 (2016).Macey, P.M., Sarma, M.K., Nagarajan, R., Aysola, R., Siegel, J.M., Harper, R.M., et al., 2016. Obstructive sleep ...
Struggle events are associated with enhanced glutamatergic- and decreased GABAergic signaling in the insular cortex, indicating the involvement of a larger ... JR Luchsinger,TL Fetterly,KM Williford,... - 《Nature Communications》 被引量: 0发表: 2021年 Obstructive sleep apnea is associated with al...
A, P values were significant in men and women (P < .001), older and younger participants (P < .001), urban communities (P < .001), rural communities (P = .004), high-income communities (HICs, P < .001), upper–middle-income communities (UMICs, P <...
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Functional mapping of rodent and human islets containing proportionally more PDX1HIGH and MAFAHIGHβ-cells reveals defects in metabolism, ionic fluxes and insulin secretion. At the transcriptomic level, the presence of increased numbers of PDX1HIGH and MAFAHIGHβ-cells leads to dysregulation of gene...
6D). Lastly, ACSL6-related genes were implicated in synaptic signaling and neurotransmission, enriched in pathways involving glutamatergic, GABAergic and serotonergic synapse pathways (Fig. 6E). Additionally, a PPI network was constructed using the GeneMANIA database, revealing the 20 most frequently ...
hypothesized to act on GABAergic circuits oxybate to patients; (2) initiating low- within the brain. GHB enhances sleep/wake sodium oxybate for adult narcolepsy and state stability, thereby improving EDS and pre- idiopathic hypersomnia; (3) addressing ...
Muzigaba, S. Xapa, N. Gobile, K. Ndayi, B. Jwili, K. Ndibaza, B. Egbujie; Sahlgrenska Academy, University of Gothenburg, Sweden: A. Rosengren, K. Bengtsson Boström, A. Rawshani, A. Gustavsson, M. Andreasson, L. Wirdemann; Pamoja Tunaweza Health Research Centre, Moshi, ...
High-dose alcohol intoxication is commonly associated with impaired inhibition, but the boundary conditions, as well as associated neurocognitive/neuroanatomical changes have remained rather unclear. This study was motivated by the counterintuitive findi
In addition, preliminary evidence14 suggests that testosterone has short- and long-term γ-aminobutyric acid (GABA)-ergic properties, and these actions may further contribute to the modulation of mood in men. Pope et al15 found that 8 of 50 men aged 20 to 50 years treated with high doses...