Merklinger-Gruchala A, Ellison PT, Lipson SF, Thune I, Jasienska G. Low estradiol levels in women of reproductive age having low sleep variation.Eur J. Cancer Prev. 2008;17(5):467-72.Merklinger-Gruchala A et al - 2008, Low estradiol levels in women of reproductive age h...
Objective To determine the efficacy and tolerability of low-dose oral 17β-estradiol and low-dose venlafaxine extended release in alleviating vasomotor symptoms (VMS). Design, Setting, and Participants In total, 339 perimenopausal and postmenopausal women with at least 2 bothersome VMS per day (mean...
Low-dose oral estradiol and venlafaxine are effective treatments for VMS in women during midlife. While the efficacy of low-dose estradiol may be slightly superior to that of venlafaxine, the difference is small and of uncertain clinical relevance. clinicaltrials.gov Identifier: NCT01418209. ...
Estradiol is the primary sex hormone in premenopausal women and people AFAB. Premenopause is the time from your first period until you enter perimenopause -- the stage just before menopause. Estradiol is formed from developing ovarian follicles. It's responsible for female characteristics and sexual ...
2. Although the occurrence of vulvovaginal atrophy and increased vaginal pH are nearly universal in menopause, most elderly women do not present with genital complaints, which suggests there are unknown factors that distinguish AV patients and asymptomatic women. So far the preferred treatment of AV...
CONCLUSIONS AND RELEVANCE: Low-dose oral estradiol and venlafaxine are effective treatments for VMS in women during midlife. While the efficacy of low-dose estradiol may be slightly superior to that of venlafaxine, the difference is small and of uncertain clinical relevance. TRIAL REGISTRATION: ...
OBJECTIVE: To evaluate the efficacy of two vaginal doses of estradiol (E2) compared with placebo in the treatment of atrophic vaginitis. METHODS: In a multi-center, randomized, double-blind, parallel-group study, 230 postmenopausal women received treatment with 25 mcg or 10 mcg E2 or placebo ...
Physiologically high levels of estradiol influ- estradiol could have effects on hippocampus-dependent ence contextual fear conditioning negatively, as female rats contextual fear conditioning. in proestrus or treatment with high estradiol reduces the Estradiol's effects on behavior may be linked to its ...
Introduction: Intra-vaginal estradiol (E2) is effective to treat symptomatic vaginal atrophy. However, in postmenopausal (PM) women on aromatase inhibitors (AI), this increases serum E2 levels. We here report pharmacokinetic (PK), effica... P Neven,G Donders,M Mögele,... - 《Cancer Resear...
In premenopausal women, the low-fat diet appeared to decrease levels of both non-protein-bound estradiol (1.48 down to 1.27%; P = .07) and non-protein-bound testosterone (1.06 down to 0.86%; P = .11). Cholesterol levels were lowered by the low-fat diet and were significantly associated...