This conclusion was supported by the highly significant increase in the ratio of plasma 17 alpha-hydroxyprogesterone to androstenedione observed between 2 and 24 h after drug administration. The effect of ketoconazole at this dose level appeared relatively specific, since no decrements in plasma ...
18 In a subset of patients, additional steroid hormones were measured by LC-MS: cortisone, 11-deoxycortisol, 17-hydroxyprogesterone, androstenedione, and corticosterone. CBG and albumin concentrations (Siemens Advia 2400) were analyzed. SST using 250 μg adrenocorticotrophic hormone intravenously (Syn...
Peak cortisol, 17-hydroxyprogesterone (17-OHP) and DHEAS responses were similar in LDT and SDT while 11-deoxycortisol responses to LDT (15.7 +/- 1.8 nmol/L) were significantly (p < 0.005) lower than the results obtained after SDT (76.3 +/- 21.4 nmol/L) in women with 11- beta OH ...
The SW form was diagnosed in all cases and 6 developed a salt-wasting crisis with severe electrolyte imbalance at D17 of life (median). Two females presented with virilization of the external genitalia (III and V Prader score). The median serum values found were: 17-hydroxyprogesterone 614ng...
(a) Cholesterol; (b) corticosterone; (c) deoxycorticosterone; (d) progesterone; (e) hydroxyprogesterone; (f) 15(S)-HETE; (g) leukotriene B4. Plasma samples from the test (No. 27 in Table 1) were pooled for each treatment (n = 1) and analysed. Full size image Discussion In ...
In congenital 17α-hydroxylase deficiency, the ratio between progesterone and 17α-hydroxyprogesterone is abnormal, with progesterone increasing and 17α-hydroxyprogesterone decreasing. Chemical properties White powder solid production method Pregnenediolone acetate is prepared by catalytic hydrogenation, alkali...
Effect of 17alpha-hydroxyprogesterone caproate on glucose intolerance in pregnancy To estimate whether 17alpha-hydroxyprogesterone caproate treatment in pregnancy increases the frequency of abnormal glucose screening and gestational diabetes mellitus (GDM).This is a retrospective cohort study of women treated ...
The labeled steroid used in the radioimmunoassay (RIA) was methyl-17α-hydroxyprogesterone acetate, 6α-[1,2-3 H(N)]- obtained from NEN (CAT NO: NET 480) while the reference preparation was medroxyprogesterone acetate (MPA) obtained from Steraloids. The assay buffer used was 0.1% gelatin ...
A booster injection of hCG (0.5 IU/g BW) was administered to each of 4 females exhibiting maximum ovarian oocyte diameter exceeding 850 μm at 9 weeks after the injection, followed by an injection of 17α-hydroxyprogesterone (2 μg/g BW) one day later for induction of ovulation. One of...
Effects of low doses of salmon gonadotropin (SG-G100) and three steroids - 17α,20β-dihydroxyprogesterone (17α,20β-diOHprog), deoxycorticosterone (DOC) and progesterone - individually, or combinations of steroid with SG-G100, on ovulation and hatching in Clarias batrachus (L.) were ...